"DNA Restriction Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.
| Descriptor ID |
D004262
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| MeSH Number(s) |
D08.811.150.280 D08.811.277.352.335.350.300 D08.811.277.352.355.325.300
|
| Concept/Terms |
DNA Restriction Enzymes- DNA Restriction Enzymes
- Enzymes, DNA Restriction
- Restriction Enzymes, DNA
- Restriction Endonucleases
- Endonucleases, Restriction
- Restriction Endonuclease
- Endonuclease, Restriction
- DNA Restriction Enzyme
- Restriction Enzyme, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Restriction Enzymes".
Below are MeSH descriptors whose meaning is more specific than "DNA Restriction Enzymes".
This graph shows the total number of publications written about "DNA Restriction Enzymes" by people in this website by year, and whether "DNA Restriction Enzymes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Restriction Enzymes" by people in Profiles.
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Mercuric ion inhibition of eukaryotic transcription factor binding to DNA. Biochem Pharmacol. 2001 Jun 15; 61(12):1543-50.
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Construction of antibiotic resistance cassettes with multiple paired restriction sites for insertional mutagenesis of Haemophilus influenzae. FEMS Microbiol Lett. 1998 Jan 01; 158(1):57-60.
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Some gene variants for 5 S RNA are dispersed in the rat genome. J Biol Chem. 1986 Aug 15; 261(23):10618-23.
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Transcriptional role for the nontranscribed spacer of rat ribosomal DNA. Mol Cell Biol. 1986 Aug; 6(8):2766-73.
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Amplified DNA of the Novikoff hepatoma nucleolus is arranged in a 7.3-kilobase tandem repeat. Biochemistry. 1985 Jul 16; 24(15):4229-33.
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Molecular cloning and expression of gene fragments from corynebacteriophage beta encoding enzymatically active peptides of diphtheria toxin. J Bacteriol. 1983 Nov; 156(2):680-5.
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Transcription initiation site of rat ribosomal DNA. Nucleic Acids Res. 1982 Nov 25; 10(22):7345-62.
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Nucleotide sequence of the region between the 18S rRNA sequence and the 28S rRNA sequence of rat ribosomal DNA. Nucleic Acids Res. 1982 Jun 25; 10(12):3667-80.
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Isolation and characterization of rat ribosomal DNA clones. Gene. 1982 Jan; 17(1):75-7.
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Cloning and characterization of a highly reiterated 5.8-kilobase pair nucleolar EcoRI DNA fragment found in Novikoff hepatoma ascites cells. Biochemistry. 1981 Feb 17; 20(4):762-5.