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Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema.
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Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema.
Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema. J Mol Med (Berl). 2011 Jun; 89(6):577-93.
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subject areas
Adenosine Triphosphatases
Adenosine Triphosphatases
Aged
Aged
Animals
Animals
Apoptosis
Apoptosis
Bronchi
Bronchi
Cell Cycle Proteins
Cell Cycle Proteins
Cinnamates
Cinnamates
Endopeptidases
Endopeptidases
Epithelial Cells
Epithelial Cells
Female
Female
HEK293 Cells
HEK293 Cells
Histone Deacetylase 2
Histone Deacetylase 2
Humans
Humans
Male
Male
Mice
Mice
Middle Aged
Middle Aged
NF-E2-Related Factor 2
NF-E2-Related Factor 2
NF-kappa B
NF-kappa B
Oxidative Stress
Oxidative Stress
Proteins
Proteins
Proteostasis Deficiencies
Proteostasis Deficiencies
Pulmonary Disease, Chronic Obstructive
Pulmonary Disease, Chronic Obstructive
Pulmonary Emphysema
Pulmonary Emphysema
Receptors, Autocrine Motility Factor
Receptors, Autocrine Motility Factor
Receptors, Cytokine
Receptors, Cytokine
Smoking
Smoking
Thiourea
Thiourea
Transcription Factor CHOP
Transcription Factor CHOP
Ubiquitin Thiolesterase
Ubiquitin Thiolesterase
Ubiquitinated Proteins
Ubiquitinated Proteins
Ubiquitin-Protein Ligases
Ubiquitin-Protein Ligases
Valosin Containing Protein
Valosin Containing Protein