"Colforsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
| Descriptor ID |
D005576
|
| MeSH Number(s) |
D02.455.849.291.300
|
| Concept/Terms |
Colforsin- Colforsin
- N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
- Coleonol
- Forskolin
|
Below are MeSH descriptors whose meaning is more general than "Colforsin".
Below are MeSH descriptors whose meaning is more specific than "Colforsin".
This graph shows the total number of publications written about "Colforsin" by people in this website by year, and whether "Colforsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Colforsin" by people in Profiles.
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MicroRNA 221 expression in theca and granulosa cells: hormonal regulation and function. J Anim Sci. 2018 Mar 06; 96(2):641-652.
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Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics. Oncologist. 2012; 17(2):220-32.
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Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells. Diabetologia. 2011 Feb; 54(2):390-402.
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Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation. J Biol Chem. 2006 Mar 24; 281(12):7784-92.
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Altered excitability of intestinal neurons in primary culture caused by acute oxidative stress. J Neurophysiol. 2003 Jun; 89(6):3039-50.
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PKA-mediated inhibition of a novel K+ channel underlies the slow after-hyperpolarization in enteric AH neurons. J Physiol. 2003 May 01; 548(Pt 3):801-14.
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Assessing opioid regulation of adenylyl cyclase activity in intact cells. Methods Mol Med. 2003; 84:29-37.
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Forskolin suppresses insulin gene transcription in islet beta-cells through a protein kinase A-independent pathway. Cell Signal. 2003 Jan; 15(1):27-35.
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Conditioning of beta(1)-adrenoceptor effect via beta(2)-subtype on L-type Ca(2+) current in canine ventricular myocytes. Am J Physiol Heart Circ Physiol. 2000 Sep; 279(3):H1329-37.
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Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev Biol. 1999 Jun 01; 210(1):56-70.