"Mast Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
| Descriptor ID |
D008407
|
| MeSH Number(s) |
A11.329.427 A15.382.652
|
| Concept/Terms |
Mast Cells- Mast Cells
- Cell, Mast
- Cells, Mast
- Mast Cell
- Basophils, Tissue
- Basophil, Tissue
- Tissue Basophil
- Tissue Basophils
|
Below are MeSH descriptors whose meaning is more general than "Mast Cells".
Below are MeSH descriptors whose meaning is more specific than "Mast Cells".
This graph shows the total number of publications written about "Mast Cells" by people in this website by year, and whether "Mast Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Mast Cells" by people in Profiles.
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Idiopathic mast cell activation syndrome and radiation therapy: a case study, literature review, and discussion of mast cell disorders and radiotherapy. Radiat Oncol. 2019 Dec 09; 14(1):222.
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Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment. Kidney Int. 2020 03; 97(3):516-527.
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The Role of Mast Cells in Intracerebral Hemorrhage. Neurocrit Care. 2018 06; 28(3):288-295.
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Granulocytes in Ocular HSV-1 Infection: Opposing Roles of Mast Cells and Neutrophils. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):3763-75.
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Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis. J Clin Invest. 2014 Oct; 124(10):4577-89.
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Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice. J Immunol. 2014 Jul 15; 193(2):477-84.
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Generation of a new congenic mouse strain with enhanced chymase expression in mast cells. PLoS One. 2013; 8(12):e84340.
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Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis. PLoS One. 2012; 7(4):e34077.
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Intravesical chondroitin sulfate inhibits recruitment of inflammatory cells in an acute acid damage "leaky bladder" model of cystitis. Urology. 2012 Feb; 79(2):483.e13-7.
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Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation. BMC Immunol. 2007 Aug 17; 8:17.