"Ouabain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
Descriptor ID |
D010042
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MeSH Number(s) |
D04.210.500.155.580.130.750.600 D09.408.180.810.600
|
Concept/Terms |
Ouabain- Ouabain
- G-Strophanthin
- G Strophanthin
- Acocantherin
- Acolongifloroside K
|
Below are MeSH descriptors whose meaning is more general than "Ouabain".
Below are MeSH descriptors whose meaning is more specific than "Ouabain".
This graph shows the total number of publications written about "Ouabain" by people in this website by year, and whether "Ouabain" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1992 | 0 | 1 | 1 |
2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ouabain" by people in Profiles.
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Ward SC, Hamilton BP, Hamlyn JM. Novel receptors for ouabain: studies in adrenocortical cells and membranes. Hypertension. 2002 Feb; 39(2 Pt 2):536-42.
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Chen CL, Sangiah S, Patterson E, Berlin KD, Garrison GL, Dunn W, Nan Y, Scherlag BJ, Lazzara R. Effects of BRB-I-28, a novel antiarrhythmic agent, and its derivatives on cardiac Na+,K(+)-ATPase, Mg(2+)-ATPase activities and contractile force. Res Commun Chem Pathol Pharmacol. 1992 Oct; 78(1):3-16.
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Clark MR, Rossi ME. Permeability characteristics of deoxygenated sickle cells. Blood. 1990 Nov 15; 76(10):2139-45.
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Banka VS, Scherlag BJ, Helfant RH. Contractile and electrophysiological responses to progressive digitalis toxicity. Cardiovasc Res. 1975 Jan; 9(1):65-72.
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Scherlag BJ, Abelleira JL, Narula OS, Samet P. The differential effects of ouabain on sinus, A-V nodal, His bundle, and idioventricular rhythms. Am Heart J. 1971 Feb; 81(2):227-35.
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Helfant RH, Scherlag BJ, Damato AM. Electrophysiological effects of direct current countershock before and after ouabain sensitization and after diphenylhydantoin desensitization in the dog. Circ Res. 1968 May; 22(5):615-23.
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Helfant RH, Ricciutti MA, Scherlag BJ, Damato AN. Effect of diphenylhydantoin sodium (dilantin) on myocardial A-V potassium difference. Am J Physiol. 1968 Apr; 214(4):880-4.
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Helfant RH, Scherlag BJ, Damato AN. Diphenylhydantoin prevention of arrhythmias in the digitalis-sensitized dog after direct-current cardioversion. Circulation. 1968 Mar; 37(3):424-8.