"ADAMTS13 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in the ADAMTS13 gene have been identified in familial cases of PURPURA, THROMBOTIC THROMBOCYTOPENIC and defects in ADAMTS13 activity are associated with MYOCARDIAL INFARCTION; BRAIN ISCHEMIA; PRE-ECLAMPSIA; and MALARIA.
| Descriptor ID |
D000071120
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.500.813 D09.400.430.500.500.813 D12.776.395.033.500.813 D12.776.860.300.085.813
|
| Concept/Terms |
ADAMTS13 Protein- ADAMTS13 Protein
- von Willebrand Factor-Cleaving Protease
- von Willebrand Factor Cleaving Protease
- ADAMTS13 Protease
- vWF-Cleaving Protease
- vWF Cleaving Protease
- ADAMTS-13 Protein
- ADAMTS 13 Protein
- A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 Protein
|
Below are MeSH descriptors whose meaning is more general than "ADAMTS13 Protein".
Below are MeSH descriptors whose meaning is more specific than "ADAMTS13 Protein".
This graph shows the total number of publications written about "ADAMTS13 Protein" by people in this website by year, and whether "ADAMTS13 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 7 | 7 |
| 2009 | 0 | 8 | 8 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 5 | 5 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 2 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 0 | 5 | 5 |
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Below are the most recent publications written about "ADAMTS13 Protein" by people in Profiles.
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Zheng XL, Vesely SK, Cataland SR, Coppo P, Geldziler B, Iorio A, Matsumoto M, Mustafa RA, Pai M, Rock G, Russell L, Tarawneh R, Valdes J, Peyvandi F. ISTH guidelines for treatment of thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020 10; 18(10):2496-2502.
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Zheng XL, Vesely SK, Cataland SR, Coppo P, Geldziler B, Iorio A, Matsumoto M, Mustafa RA, Pai M, Rock G, Russell L, Tarawneh R, Valdes J, Peyvandi F. Good practice statements (GPS) for the clinical care of patients with thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020 10; 18(10):2503-2512.
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Zheng XL, Vesely SK, Cataland SR, Coppo P, Geldziler B, Iorio A, Matsumoto M, Mustafa RA, Pai M, Rock G, Russell L, Tarawneh R, Valdes J, Peyvandi F. ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020 10; 18(10):2486-2495.
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Kremer Hovinga JA, George JN. Hereditary Thrombotic Thrombocytopenic Purpura. Reply. N Engl J Med. 2020 01 23; 382(4):394-395.
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Sukumar S, George JN, Cataland SR. Shared decision making, thrombotic thrombocytopenic purpura, and caplacizumab. Am J Hematol. 2020 04; 95(4):E76-E77.
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Kremer Hovinga JA, George JN. Hereditary Thrombotic Thrombocytopenic Purpura. N Engl J Med. 2019 10 24; 381(17):1653-1662.
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George JN. Congenital TTP: toward a turning point. Blood. 2019 04 11; 133(15):1615-1617.
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van Dorland HA, Taleghani MM, Sakai K, Friedman KD, George JN, Hrachovinova I, Knöbl PN, von Krogh AS, Schneppenheim R, Aebi-Huber I, Bütikofer L, Largiadèr CR, Cermakova Z, Kokame K, Miyata T, Yagi H, Terrell DR, Vesely SK, Matsumoto M, Lämmle B, Fujimura Y, Kremer Hovinga JA. The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017. Haematologica. 2019 10; 104(10):2107-2115.
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Saleem R, Rogers ZR, Neunert C, George JN. Maintenance rituximab for relapsing thrombotic thrombocytopenic purpura: a case report. Transfusion. 2019 03; 59(3):921-926.
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George JN. The remarkable diversity of thrombotic thrombocytopenic purpura: a perspective. Blood Adv. 2018 06 26; 2(12):1510-1516.