"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
Descriptor ID 
D000075082

MeSH Number(s) 
H01.770.644.578

Concept/Terms 
Proof of Concept Study Proof of Concept Study
 Concept Study Proof
 Study Proof, Concept
 Proof of Concept Investigation
 Concept Investigation Proof
 Investigation Proof, Concept
 Proof of Concept Research
 Concept Research Proof
 Concept Research Proofs
 Research Proof, Concept
 Proof of Concept Testing
 Concept Testing Proof
 Concept Testing Proofs
 Testing Proof, Concept
 Testing Proofs, Concept
 Proof of Concept Experiment
 Concept Experiment Proof
 Concept Experiment Proofs
 Experiment Proof, Concept
 Proof of Concept Approach
 Approach Proof, Concept
 Approach Proofs, Concept
 Concept Approach Proof
 Concept Approach Proofs
 Proof of Concept Studies
Proof of Concept Prototype Proof of Concept Prototype
 Concept Prototype Proof
 Concept Prototype Proofs
 Prototype Proof, Concept
 Proof of Concept Model
 Concept Model Proof
 Concept Model Proofs
 Model Proof, Concept
Proof of Concept Evaluation Proof of Concept Evaluation
 Concept Evaluation Proof
 Concept Evaluation Proofs
 Evaluation Proof, Concept
 Proof of Concept Demonstration
 Concept Demonstration Proof
 Demonstration Proof, Concept

Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
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Year  Major Topic  Minor Topic  Total 

2017  0  1  1 
2018  0  1  1 
2019  0  2  2 
2020  0  2  2 
2021  0  2  2 
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Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.

LowLevel Tragus Stimulation Modulates Atrial Alternans and Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation. J Am Heart Assoc. 2021 06 15; 10(12):e020865.

CalciumInduced Autonomic Denervation in Patients With PostOperative Atrial Fibrillation. J Am Coll Cardiol. 2021 01 05; 77(1):5767.

Prevent breaking bad: A proof of concept study of rebalancing the brain's rumination circuit with realtime fMRI functional connectivity neurofeedback. Hum Brain Mapp. 2021 03; 42(4):922940.

Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma. AJNR Am J Neuroradiol. 2020 07; 41(7):11931200.

Towards early monitoring of chemotherapyinduced drug resistance based on single cell metabolomics: Combining singleprobe mass spectrometry with machine learning. Anal Chim Acta. 2019 Dec 27; 1092:4248.

Dendrimer grafted albumin nanoparticles for the treatment of post cerebral stroke damages: A proof of concept study. Colloids Surf B Biointerfaces. 2019 Dec 01; 184:110488.

3D printing and intraoperative neuronavigation tailoring for skull base reconstruction after extended endoscopic endonasal surgery: proof of concept. J Neurosurg. 2018 03 02; 130(1):248255.

LowLevel Tragus Stimulation for the Treatment of Ischemia and Reperfusion Injury in Patients With STSegment Elevation Myocardial Infarction: A ProofofConcept Study. JACC Cardiovasc Interv. 2017 08 14; 10(15):15111520.