Angiotensin II

"Angiotensin II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Descriptor ID	D000804
MeSH Number(s)	D06.472.699.094.078 D12.644.400.070.078 D12.644.456.073.041 D12.644.548.058.078 D12.776.631.650.070.078 D23.469.050.050.050
Concept/Terms	Angiotensin II Angiotensin II ANG-(1-8)Octapeptide Angiotensin-(1-8) Octapeptide Angiotensin II, Val(5)- Angiotensin II, Val(5)- Angiotensin II, Valine(5)- Valyl(5)-Angiotensin II Angiotensin II, Ile(5)- Angiotensin II, Ile(5)- Angiotensin II, Isoleucine(5)- 5-L-Isoleucine Angiotensin II 5 L Isoleucine Angiotensin II Angiotensin II, 5-L-Isoleucine Isoleucine(5)-Angiotensin Isoleucyl(5)-Angiotensin II

Below are MeSH descriptors whose meaning is more general than "Angiotensin II".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Angiotensins [D06.472.699.094]
Angiotensin II [D06.472.699.094.078]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Angiotensins [D12.644.400.070]
Angiotensin II [D12.644.400.070.078]
Oligopeptides [D12.644.456]
Angiotensins [D12.644.456.073]
Angiotensin II [D12.644.456.073.041]
Peptide Hormones [D12.644.548]
Angiotensins [D12.644.548.058]
Angiotensin II [D12.644.548.058.078]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Angiotensins [D12.776.631.650.070]
Angiotensin II [D12.776.631.650.070.078]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Angiotensins [D23.469.050.050]
Angiotensin II [D23.469.050.050.050]

Below are MeSH descriptors whose meaning is related to "Angiotensin II".

Below are MeSH descriptors whose meaning is more specific than "Angiotensin II".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiotensin II" by people in this website by year, and whether "Angiotensin II" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
2002	0	1	1
2004	0	2	2
2006	1	1	2
2008	0	1	1
2010	1	0	1
2012	0	1	1
2013	1	2	3
2014	0	1	1
2015	1	1	2
2016	0	1	1
2017	0	1	1
2019	0	1	1

Below are the most recent publications written about "Angiotensin II" by people in Profiles.

Tarantini S, Yabluchanskiy A, Lindsey ML, Csiszar A, Ungvari Z. Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619.

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Heavner MS, McCurdy MT, Mazzeffi MA, Galvagno SM, Tanaka KA, Chow JH. Angiotensin II and Vasopressin for Vasodilatory Shock: A Critical Appraisal of Catecholamine-Sparing Strategies. J Intensive Care Med. 2021 Jun; 36(6):635-645.

View in: PubMed
Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.

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Chow JH, Galvagno SM, Tanaka KA, Mazzeffi MA, Chancer Z, Henderson R, McCurdy MT. When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report. A A Pract. 2018 Oct 01; 11(7):175-180.

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Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Springo Z, Fulop GA, Ashpole N, Gautam T, Giles CB, Wren JD, Sonntag WE, Csiszar A, Ungvari Z. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.

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Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.

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Liles C, Li H, Veitla V, Liles JT, Murphy TA, Cunningham MW, Yu X, Kem DC. AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction. Hypertension. 2015 Oct; 66(4):830-5.

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Toth P, Tucsek Z, Tarantini S, Sosnowska D, Gautam T, Mitschelen M, Koller A, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.

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Toth P, Csiszar A, Tucsek Z, Sosnowska D, Gautam T, Koller A, Schwartzman ML, Sonntag WE, Ungvari Z. Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708.

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Dikalov SI, Ungvari Z. Role of mitochondrial oxidative stress in hypertension. Am J Physiol Heart Circ Physiol. 2013 Nov 15; 305(10):H1417-27.

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