Angiotensin II

"Angiotensin II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Descriptor ID	D000804
MeSH Number(s)	D06.472.699.094.078 D12.644.400.070.078 D12.644.456.073.041 D12.644.548.058.078 D12.776.631.650.070.078 D23.469.050.050.050
Concept/Terms	Angiotensin II Angiotensin II ANG-(1-8)Octapeptide Angiotensin-(1-8) Octapeptide Angiotensin II, Val(5)- Angiotensin II, Val(5)- Angiotensin II, Valine(5)- Valyl(5)-Angiotensin II Angiotensin II, Ile(5)- Angiotensin II, Ile(5)- Angiotensin II, Isoleucine(5)- 5-L-Isoleucine Angiotensin II 5 L Isoleucine Angiotensin II Angiotensin II, 5-L-Isoleucine Isoleucine(5)-Angiotensin Isoleucyl(5)-Angiotensin II

Below are MeSH descriptors whose meaning is more general than "Angiotensin II".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Angiotensins [D06.472.699.094]
Angiotensin II [D06.472.699.094.078]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Angiotensins [D12.644.400.070]
Angiotensin II [D12.644.400.070.078]
Oligopeptides [D12.644.456]
Angiotensins [D12.644.456.073]
Angiotensin II [D12.644.456.073.041]
Peptide Hormones [D12.644.548]
Angiotensins [D12.644.548.058]
Angiotensin II [D12.644.548.058.078]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Angiotensins [D12.776.631.650.070]
Angiotensin II [D12.776.631.650.070.078]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Angiotensins [D23.469.050.050]
Angiotensin II [D23.469.050.050.050]

Below are MeSH descriptors whose meaning is related to "Angiotensin II".

Below are MeSH descriptors whose meaning is more specific than "Angiotensin II".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiotensin II" by people in this website by year, and whether "Angiotensin II" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
2002	0	1	1
2004	0	2	2
2006	1	1	2
2008	0	1	1
2010	1	0	1
2012	0	1	1
2013	1	2	3
2014	0	1	1
2015	1	1	2
2016	0	1	1
2017	0	1	1
2019	0	1	1

Below are the most recent publications written about "Angiotensin II" by people in Profiles.

Heavner MS, McCurdy MT, Mazzeffi MA, Galvagno SM, Tanaka KA, Chow JH. Angiotensin II and Vasopressin for Vasodilatory Shock: A Critical Appraisal of Catecholamine-Sparing Strategies. J Intensive Care Med. 2021 Jun; 36(6):635-645.

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Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.

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Chow JH, Galvagno SM, Tanaka KA, Mazzeffi MA, Chancer Z, Henderson R, McCurdy MT. When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report. A A Pract. 2018 Oct 01; 11(7):175-180.

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Flevaris P, Khan SS, Eren M, Schuldt AJT, Shah SJ, Lee DC, Gupta S, Shapiro AD, Burridge PW, Ghosh AK, Vaughan DE. Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-ß and Cardiac Fibrosis. Circulation. 2017 Aug 15; 136(7):664-679.

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Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Springo Z, Fulop GA, Ashpole N, Gautam T, Giles CB, Wren JD, Sonntag WE, Csiszar A, Ungvari Z. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.

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Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.

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Liles C, Li H, Veitla V, Liles JT, Murphy TA, Cunningham MW, Yu X, Kem DC. AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction. Hypertension. 2015 Oct; 66(4):830-5.

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Toth P, Tucsek Z, Tarantini S, Sosnowska D, Gautam T, Mitschelen M, Koller A, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.

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Toth P, Csiszar A, Tucsek Z, Sosnowska D, Gautam T, Koller A, Schwartzman ML, Sonntag WE, Ungvari Z. Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708.

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Dikalov SI, Ungvari Z. Role of mitochondrial oxidative stress in hypertension. Am J Physiol Heart Circ Physiol. 2013 Nov 15; 305(10):H1417-27.

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