"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
| Descriptor ID |
D002110
|
| MeSH Number(s) |
D03.132.960.175 D03.633.100.759.758.824.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in this website by year, and whether "Caffeine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 5 | 0 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caffeine" by people in Profiles.
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Starr MC, Charlton JR, Guillet R, Reidy K, Tipple TE, Jetton JG, Kent AL, Abitbol CL, Ambalavanan N, Mhanna MJ, Askenazi DJ, Selewski DT, Harer MW. Advances in Neonatal Acute Kidney Injury. Pediatrics. 2021 11; 148(5).
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Salatto RW, Arevalo JA, Brown LE, Wiersma LD, Coburn JW. Caffeine's Effects on an Upper-Body Resistance Exercise Workout. J Strength Cond Res. 2020 Jun; 34(6):1643-1648.
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Doepker C, Franke K, Myers E, Goldberger JJ, Lieberman HR, O'Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D. Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children. Nutrients. 2018 Oct 18; 10(10).
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Wikoff D, Welsh BT, Henderson R, Brorby GP, Britt J, Myers E, Goldberger J, Lieberman HR, O'Brien C, Peck J, Tenenbein M, Weaver C, Harvey S, Urban J, Doepker C. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017 Nov; 109(Pt 1):585-648.
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Black CD, Gonglach AR, Renfroe JB, Hight RE. The effects of caffeine ingestion on exercise-induced hypoalgesia: A pilot study. Physiol Behav. 2016 07 01; 161:1-6.
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Gonglach AR, Ade CJ, Bemben MG, Larson RD, Black CD. Muscle Pain as a Regulator of Cycling Intensity: Effect of Caffeine Ingestion. Med Sci Sports Exerc. 2016 Feb; 48(2):287-96.
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Doepker C, Lieberman HR, Smith AP, Peck JD, El-Sohemy A, Welsh BT. Caffeine: Friend or Foe? Annu Rev Food Sci Technol. 2016; 7:117-37.
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Black CD, Waddell DE, Gonglach AR. Caffeine's Ergogenic Effects on Cycling: Neuromuscular and Perceptual Factors. Med Sci Sports Exerc. 2015 Jun; 47(6):1145-58.
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Murray KA, O'Neal KS, Weisz M. Dietary suggestions for migraine prevention. Am J Health Syst Pharm. 2015 Apr 01; 72(7):519-21.
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Trevino MA, Coburn JW, Brown LE, Judelson DA, Malek MH. Acute effects of caffeine on strength and muscle activation of the elbow flexors. J Strength Cond Res. 2015 Feb; 29(2):513-20.