"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
| Descriptor ID |
D002110
|
| MeSH Number(s) |
D03.132.960.175 D03.633.100.759.758.824.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in this website by year, and whether "Caffeine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 5 | 0 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caffeine" by people in Profiles.
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The effects of caffeine supplementation on blood pressure in adults: A systematic review and dose-response meta-analysis. Clin Nutr ESPEN. 2023 12; 58:165-177.
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Advances in Neonatal Acute Kidney Injury. Pediatrics. 2021 11; 148(5).
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Caffeine's Effects on an Upper-Body Resistance Exercise Workout. J Strength Cond Res. 2020 Jun; 34(6):1643-1648.
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Caffeine enhances sustained attention among adolescents. Exp Clin Psychopharmacol. 2021 Feb; 29(1):82-89.
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Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children. Nutrients. 2018 Oct 18; 10(10).
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Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol. 2017 Nov; 109(Pt 1):585-648.
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Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle myotubes. Am J Physiol Cell Physiol. 2017 Jun 01; 312(6):C689-C696.
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The effects of caffeine ingestion on exercise-induced hypoalgesia: A pilot study. Physiol Behav. 2016 07 01; 161:1-6.
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Muscle Pain as a Regulator of Cycling Intensity: Effect of Caffeine Ingestion. Med Sci Sports Exerc. 2016 Feb; 48(2):287-96.
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Caffeine: Friend or Foe? Annu Rev Food Sci Technol. 2016; 7:117-37.