"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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The Role of Polymers and Excipients for Better Gastric Retention of Captopril. Crit Rev Ther Drug Carrier Syst. 2022; 39(6):85-106.
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Whey-Derived Peptides Interactions with ACE by Molecular Docking as a Potential Predictive Tool of Natural ACE Inhibitors. Int J Mol Sci. 2020 Jan 29; 21(3).
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Hemolytic anemia: a rare but potentially serious adverse effect of captopril. Herz. 2007 Feb; 32(1):62-4.
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Renin-dependent hypertension caused by nonfocal stenotic aberrant renal arteries: proof of a new syndrome. Hypertension. 2005 Aug; 46(2):380-5.
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Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am J Pathol. 2004 Jul; 165(1):219-26.
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Diagnostic value of the post-captopril test in primary aldosteronism. Hypertension. 2002 Apr; 39(4):935-8.
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Acute effects of captopril and ibuprofen on proteinuria in patients with nephrosis. J Lab Clin Med. 1990 Oct; 116(4):462-8.
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Interaction of captopril and ibuprofen on glomerular and tubular function in humans. Am J Physiol. 1990 Aug; 259(2 Pt 2):F233-8.
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Sodium and water excretion in nephrotic patients: effects of changes in renal haemodynamics. Clin Sci (Lond). 1990 Aug; 79(2):123-9.