Binding Sites, Antibody

"Binding Sites, Antibody" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Local surface sites on antibodies which react with antigen determinant sites on antigens (EPITOPES.) They are formed from parts of the variable regions of FAB FRAGMENTS.

Descriptor ID	D001666
MeSH Number(s)	G02.111.570.060.425.079 G02.111.570.120.408 G12.122.232 G12.125
Concept/Terms	Binding Sites, Antibody Binding Sites, Antibody Antibody Binding Site Binding Site, Antibody Paratopes Paratope Antibody Binding Sites

Below are MeSH descriptors whose meaning is more general than "Binding Sites, Antibody".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Amino Acid Sequence [G02.111.570.060]
Immunoglobulin Variable Region [G02.111.570.060.425]
Binding Sites, Antibody [G02.111.570.060.425.079]
Binding Sites [G02.111.570.120]
Binding Sites, Antibody [G02.111.570.120.408]
Immune System Phenomena [G12]
Antigen-Antibody Reactions [G12.122]
Binding Sites, Antibody [G12.122.232]
Binding Sites, Antibody [G12.125]

Below are MeSH descriptors whose meaning is related to "Binding Sites, Antibody".

Below are MeSH descriptors whose meaning is more specific than "Binding Sites, Antibody".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Binding Sites, Antibody" by people in this website by year, and whether "Binding Sites, Antibody" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 2 publications in 1998 and 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1996	1	0	1
1997	1	0	1
1998	1	1	2
1999	0	2	2
2000	0	1	1
2007	0	1	1
2015	0	1	1

Below are the most recent publications written about "Binding Sites, Antibody" by people in Profiles.

Whitby PW, Seale TW, Morton DJ, Stull TL. Antisera Against Certain Conserved Surface-Exposed Peptides of Nontypeable Haemophilus influenzae Are Protective. PLoS One. 2015; 10(9):e0136867.

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Kirvan CA, Cox CJ, Swedo SE, Cunningham MW. Tubulin is a neuronal target of autoantibodies in Sydenham's chorea. J Immunol. 2007 Jun 01; 178(11):7412-21.

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Kirton CM, Laukkanen ML, Nieminen A, Merinen M, Stolen CM, Armour K, Smith DJ, Salmi M, Jalkanen S, Clark MR. Function-blocking antibodies to human vascular adhesion protein-1: a potential anti-inflammatory therapy. Eur J Immunol. 2005 Nov; 35(11):3119-30.

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Terzyan S, Ramsland PA, Voss EW, Herron JN, Edmundson AB. Three-dimensional structures of idiotypically related Fabs with intermediate and high affinity for fluorescein. J Mol Biol. 2004 Jun 18; 339(5):1141-51.

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Kurien BT, Newland J, Paczkowski C, Moore KL, Scofield RH. Association of neutropenia in systemic lupus erythematosus (SLE) with anti-Ro and binding of an immunologically cross-reactive neutrophil membrane antigen. Clin Exp Immunol. 2000 Apr; 120(1):209-17.

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Armour KL, Clark MR, Hadley AG, Williamson LM. Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities. Eur J Immunol. 1999 08; 29(8):2613-24.

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Lee LA, Walsh P, Prater CA, Su LJ, Marchbank A, Egbert TB, Dellavalle RP, Targoff IN, Kaufman KM, Chorzelski TP, Jablonska S. Characterization of an autoantigen associated with chronic ulcerative stomatitis: the CUSP autoantigen is a member of the p53 family. J Invest Dermatol. 1999 Aug; 113(2):146-51.

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Scofield RH, Farris AD, Horsfall AC, Harley JB. Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins. Arthritis Rheum. 1999 Feb; 42(2):199-209.

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Fan ZC, Shan L, Goldsteen BZ, Guddat LW, Thakur A, Landolfi NF, Co MS, Vasquez M, Queen C, Ramsland PA, Edmundson AB. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody. J Mol Recognit. 1999 Jan-Feb; 12(1):19-32.

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Pruett PS, Air GM. Critical interactions in binding antibody NC41 to influenza N9 neuraminidase: amino acid contacts on the antibody heavy chain. Biochemistry. 1998 Jul 28; 37(30):10660-70.

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