Dehydroepiandrosterone

"Dehydroepiandrosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.

Descriptor ID	D003687
MeSH Number(s)	D04.210.500.054.079.429.625 D04.210.500.578.502.400 D06.472.040.502.400 D06.472.334.851.968.952
Concept/Terms	Dehydroepiandrosterone Dehydroepiandrosterone 5-Androsten-3-beta-hydroxy-17-one 5 Androsten 3 beta hydroxy 17 one DHEA Prasterone Androstenolone Dehydroisoandrosterone Prasterone, 3 alpha-Isomer Prasterone, 3 alpha-Isomer Prasterone, 3 alpha Isomer 5-Androsten-3-ol-17-one 5-Androsten-3-ol-17-one 5 Androsten 3 ol 17 one

Below are MeSH descriptors whose meaning is more general than "Dehydroepiandrosterone".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Androstanes [D04.210.500.054]
Androstenes [D04.210.500.054.079]
Androstenols [D04.210.500.054.079.429]
Dehydroepiandrosterone [D04.210.500.054.079.429.625]
Ketosteroids [D04.210.500.578]
17-Ketosteroids [D04.210.500.578.502]
Dehydroepiandrosterone [D04.210.500.578.502.400]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Adrenal Cortex Hormones [D06.472.040]
17-Ketosteroids [D06.472.040.502]
Dehydroepiandrosterone [D06.472.040.502.400]
Gonadal Hormones [D06.472.334]
Gonadal Steroid Hormones [D06.472.334.851]
Testosterone Congeners [D06.472.334.851.968]
Dehydroepiandrosterone [D06.472.334.851.968.952]

Below are MeSH descriptors whose meaning is related to "Dehydroepiandrosterone".

Below are MeSH descriptors whose meaning is more specific than "Dehydroepiandrosterone".

Dehydroepiandrosterone
Dehydroepiandrosterone Sulfate

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dehydroepiandrosterone" by people in this website by year, and whether "Dehydroepiandrosterone" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	0	1
1994	0	1	1
2002	1	0	1
2003	1	0	1
2004	2	0	2
2005	1	0	1
2006	1	0	1
2007	1	0	1
2008	1	0	1
2009	0	1	1

Below are the most recent publications written about "Dehydroepiandrosterone" by people in Profiles.

Gupte RS, Floyd BC, Kozicky M, George S, Ungvari ZI, Neito V, Wolin MS, Gupte SA. Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver. Free Radic Biol Med. 2009 Aug 01; 47(3):219-28.

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Sawalha AH, Kovats S. Dehydroepiandrosterone in systemic lupus erythematosus. Curr Rheumatol Rep. 2008 Aug; 10(4):286-91.

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Igwebuike A, Irving BA, Bigelow ML, Short KR, McConnell JP, Nair KS. Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women. J Clin Endocrinol Metab. 2008 Feb; 93(2):534-8.

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Nair KS, Rizza RA, O'Brien P, Dhatariya K, Short KR, Nehra A, Vittone JL, Klee GG, Basu A, Basu R, Cobelli C, Toffolo G, Dalla Man C, Tindall DJ, Melton LJ, Smith GE, Khosla S, Jensen MD. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med. 2006 Oct 19; 355(16):1647-59.

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Olech E, Merrill JT. DHEA supplementation: the claims in perspective. Cleve Clin J Med. 2005 Nov; 72(11):965-6, 968, 970-1 passim.

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Petri MA, Mease PJ, Merrill JT, Lahita RG, Iannini MJ, Yocum DE, Ginzler EM, Katz RS, Gluck OS, Genovese MC, Van Vollenhoven R, Kalunian KC, Manzi S, Greenwald MW, Buyon JP, Olsen NJ, Schiff MH, Kavanaugh AF, Caldwell JR, Ramsey-Goldman R, St Clair EW, Goldman AL, Egan RM, Polisson RP, Moder KG, Rothfield NF, Spencer RT, Hobbs K, Fessler BJ, Calabrese LH, Moreland LW, Cohen SB, Quarles BJ, Strand V, Gurwith M, Schwartz KE. Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. Arthritis Rheum. 2004 Sep; 50(9):2858-68.

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Pillemer SR, Brennan MT, Sankar V, Leakan RA, Smith JA, Grisius M, Ligier S, Radfar L, Kok MR, Kingman A, Fox PC. Pilot clinical trial of dehydroepiandrosterone (DHEA) versus placebo for Sjögren's syndrome. Arthritis Rheum. 2004 Aug 15; 51(4):601-4.

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Merrill JT. Dehydroepiandrosterone, a sex steroid metabolite in development for systemic lupus erythematosus. Expert Opin Investig Drugs. 2003 Jun; 12(6):1017-25.

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Petri MA, Lahita RG, Van Vollenhoven RF, Merrill JT, Schiff M, Ginzler EM, Strand V, Kunz A, Gorelick KJ, Schwartz KE. Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial. Arthritis Rheum. 2002 Jul; 46(7):1820-9.

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Wild RA. Role of endogenous estrogen in the hirsutism paradigm. J Reprod Med. 1994 Apr; 39(4):273-6.

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