"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
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| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Phase III study of valspodar (PSC 833) combined with paclitaxel and carboplatin compared with paclitaxel and carboplatin alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary peritoneal cancer. J Clin Oncol. 2008 Jun 01; 26(16):2674-82.
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Decrease in endothelial cell-dependent protein C activation induced by thrombomodulin by treatment with cyclosporine. Transplantation. 1991 Mar; 51(3):701-5.
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Vascular response to cyclosporine and verapamil in the rat pancreas. J Surg Res. 1990 Oct; 49(4):341-3.
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Thrombosis in human pancreatic transplantation associated with elevated cyclosporine levels and possible protection by antihypertensive agents. J Okla State Med Assoc. 1990 Jun; 83(6):255-7.