Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Descriptor ID |
D004681
|
MeSH Number(s) |
C10.114.703.300 C10.228.140.695.562.250 C10.314.350.250 C20.111.258.625.300 E05.598.500.500.500
|
Concept/Terms |
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
|
Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in this website by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2008 | 2 | 0 | 2 |
2009 | 1 | 0 | 1 |
2010 | 4 | 0 | 4 |
2011 | 1 | 1 | 2 |
2012 | 4 | 1 | 5 |
2013 | 2 | 2 | 4 |
2014 | 2 | 0 | 2 |
2015 | 1 | 1 | 2 |
2016 | 2 | 0 | 2 |
2017 | 1 | 1 | 2 |
2018 | 2 | 0 | 2 |
2019 | 2 | 0 | 2 |
2020 | 1 | 0 | 1 |
2021 | 4 | 0 | 4 |
2023 | 2 | 0 | 2 |
2024 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles.
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Ferritin loss in astrocytes reduces spinal cord oxidative stress and demyelination in the experimental autoimmune encephalomyelitis (EAE) model. Glia. 2024 Dec; 72(12):2327-2343.
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females. Cell Metab. 2024 Oct 01; 36(10):2298-2314.e11.
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Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis. J Neuroinflammation. 2023 Nov 14; 20(1):263.
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Oxygen treatment reduces neurological deficits and demyelination in two animal models of multiple sclerosis. Neuropathol Appl Neurobiol. 2023 02; 49(1):e12868.
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Interferon-ß Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease. Cells. 2021 08 20; 10(8).
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Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE. Int J Mol Sci. 2021 Mar 13; 22(6).
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CNS Autoimmune Responses in BCMA-Deficient Mice Provide Insight for the Failure of Atacicept in MS. Neurol Neuroimmunol Neuroinflamm. 2021 05; 8(3).
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ELTD1 as a biomarker for multiple sclerosis: Pre-clinical molecular-targeted studies in a mouse experimental autoimmune encephalomyelitis model. Mult Scler Relat Disord. 2021 Apr; 49:102786.
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Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica. Nat Commun. 2020 06 05; 11(1):2856.
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B cell function impacts the efficacy of IFN-ß therapy in EAE. J Neuroimmunol. 2020 01 15; 338:577106.