"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
| Descriptor ID |
D005165
|
| MeSH Number(s) |
D12.776.124.125.300 D23.119.300
|
| Concept/Terms |
Factor V- Factor V
- Factor Five
- Five, Factor
- AC Globulin
- Blood Coagulation Factor V
- Factor Pi
- Proaccelerin
- Factor 5
- Coagulation Factor V
- Factor V, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor V".
Below are MeSH descriptors whose meaning is more specific than "Factor V".
This graph shows the total number of publications written about "Factor V" by people in this website by year, and whether "Factor V" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor V" by people in Profiles.
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Tanaka KA, VanDyck K, Shettar SS, Gomes M. Perioperative Management of Hereditary Factor V Deficiency: Timing of Plasma Administration is Critical in Maximizing Hemostatic Potency of Transfused Factor V. J Cardiothorac Vasc Anesth. 2022 06; 36(6):1811-1812.
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Muhsin-Sharafaldine MR, Kennedy BR, Saunderson SC, Buchanan CR, Dunn AC, Faed JM, McLellan AD. Mechanistic insight into the procoagulant activity of tumor-derived apoptotic vesicles. Biochim Biophys Acta Gen Subj. 2017 Feb; 1861(2):286-295.
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Smith SA, Comp PC, Morrissey JH. Traces of factor VIIa modulate thromboplastin sensitivity to factors V, VII, X, and prothrombin. J Thromb Haemost. 2006 Jul; 4(7):1553-8.
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Comp PC. Should coagulation tests be used to determine which oral contraceptive users have an increased risk of thrombophlebitis? Contraception. 2006 Jan; 73(1):4-5.
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Raife TJ, Lentz SR, Atkinson BS, Vesely SK, Hessner MJ. Factor V Leiden: a genetic risk factor for thrombotic microangiopathy in patients with normal von Willebrand factor-cleaving protease activity. Blood. 2002 Jan 15; 99(2):437-42.
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Comp PC. Advances in the etiology and treatment of venous thromboembolism. Adv Intern Med. 1999; 44:59-89.
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Raskob GE. Duration of anticoagulant treatment for venous thrombosis. Curr Opin Pulm Med. 1997 Jul; 3(4):286-90.
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Comp PC. Thrombophilic mechanisms of OCs. Int J Fertil Womens Med. 1997; Suppl 1:170-6.
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Esmon CT, DeBault L, Carroll RC, Comp PC, Esmon NL. Biochemical and physiological aspects of protein c. Ric Clin Lab. 1984 Jul-Sep; 14(3):455-68.
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Comp PC, Jacocks RM, Ferrell GL, Esmon CT. Activation of protein C in vivo. J Clin Invest. 1982 Jul; 70(1):127-34.