Enhancer Elements, Genetic
"Enhancer Elements, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances from a promoter.
| Descriptor ID |
D004742
|
| MeSH Number(s) |
G02.111.570.080.689.330 G05.360.080.689.330 G05.360.340.024.340.137.750.249
|
| Concept/Terms |
Enhancer Elements, Genetic- Enhancer Elements, Genetic
- Element, Genetic Enhancer
- Elements, Genetic Enhancer
- Enhancer Element, Genetic
- Genetic Enhancer Element
- Genetic Enhancer Elements
- Enhancer Elements
- Element, Enhancer
- Elements, Enhancer
- Enhancer Element
- Enhancer Sequences
- Enhancer Sequence
- Sequence, Enhancer
- Sequences, Enhancer
|
Below are MeSH descriptors whose meaning is more general than "Enhancer Elements, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Enhancer Elements, Genetic".
This graph shows the total number of publications written about "Enhancer Elements, Genetic" by people in this website by year, and whether "Enhancer Elements, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Enhancer Elements, Genetic" by people in Profiles.
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Cooper SE, Schwartzentruber J, Bello E, Coomber EL, Bassett AR. Screening for functional transcriptional and splicing regulatory variants with GenIE. Nucleic Acids Res. 2020 12 16; 48(22):e131.
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Jasenosky LD, Nambu A, Tsytsykova AV, Ranjbar S, Haridas V, Kruidenier L, Tough DF, Goldfeld AE. Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells. J Immunol. 2020 11 01; 205(9):2479-2488.
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Molineros JE, Singh B, Terao C, Okada Y, Kaplan J, McDaniel B, Akizuki S, Sun C, Webb CF, Looger LL, Nath SK. Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility. Front Immunol. 2019; 10:1066.
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Siefert JC, Georgescu C, Wren JD, Koren A, Sansam CL. DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation. Genome Res. 2017 08; 27(8):1406-1416.
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Wang S, Wen F, Tessneer KL, Gaffney PM. TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus. Genes Immun. 2016 04; 17(3):165-70.
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Dozmorov MG, Wren JD, Alarcón-Riquelme ME. Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes. Epigenetics. 2014 Feb; 9(2):276-85.
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Wang S, Wen F, Wiley GB, Kinter MT, Gaffney PM. An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. PLoS Genet. 2013; 9(9):e1003750.
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Kothapalli NR, Collura KM, Norton DD, Fugmann SD. Separation of mutational and transcriptional enhancers in Ig genes. J Immunol. 2011 Sep 15; 187(6):3247-55.
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Fore TR, Ojwang AA, Warner ML, Peng X, Bohm RA, Welch WP, Goodnight LK, Bao H, Zhang B. Mapping and application of enhancer-trap flippase expression in larval and adult Drosophila CNS. J Vis Exp. 2011 Jun 03; (52).
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Kothapalli NR, Norton DD, Fugmann SD. Classical Mus musculus Ig? enhancers support transcription but not high level somatic hypermutation from a V-lambda promoter in chicken DT40 cells. PLoS One. 2011 Apr 20; 6(4):e18955.