"Epidermal Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
| Descriptor ID |
D004815
|
| MeSH Number(s) |
D06.472.317.350 D12.644.276.382.500 D12.776.467.382.500 D23.529.382.500
|
| Concept/Terms |
Epidermal Growth Factor- Epidermal Growth Factor
- Growth Factor, Epidermal
- Urogastrone
- Epidermal Growth Factor-Urogastrone
- Growth Factor-Urogastrone, Epidermal
- Human Urinary Gastric Inhibitor
- beta-Urogastrone
- beta Urogastrone
- EGF
|
Below are MeSH descriptors whose meaning is more general than "Epidermal Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Epidermal Growth Factor".
This graph shows the total number of publications written about "Epidermal Growth Factor" by people in this website by year, and whether "Epidermal Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epidermal Growth Factor" by people in Profiles.
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Decursin inhibits EGFR-ERK1/2 signaling axis in advanced human prostate carcinoma cells. Prostate. 2023 May; 83(6):534-546.
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Effects of transforming growth factor β1 on steroidogenesis of feline granulosa cells cultured in vitro. Reprod Fertil Dev. 2022 Jul; 34(11):789-797.
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Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. Cells. 2019 05 29; 8(6).
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Burn wounds in the young versus the aged patient display differential immunological responses. Burns. 2018 09; 44(6):1475-1481.
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An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors. PLoS One. 2014; 9(9):e106901.
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Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors a- and ß-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft. Steroids. 2013 Nov; 78(11):1071-86.
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Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis. J Biol Chem. 2012 Jan 02; 287(1):712-722.
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EGFR and HER-2/neu expression in invasive apocrine carcinoma of the breast. Mod Pathol. 2010 May; 23(5):644-53.
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Optical molecular imaging of epidermal growth factor receptor expression to improve detection of oral neoplasia. Neoplasia. 2009 Jun; 11(6):542-51.
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Oligonucleotide-coated metallic nanoparticles as a flexible platform for molecular imaging agents. Bioconjug Chem. 2007 Nov-Dec; 18(6):2090-6.