Herpesvirus 4, Human

"Herpesvirus 4, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The type species of LYMPHOCRYPTOVIRUS, subfamily GAMMAHERPESVIRINAE, infecting B-cells in humans. It is thought to be the causative agent of INFECTIOUS MONONUCLEOSIS and is strongly associated with oral hairy leukoplakia (LEUKOPLAKIA, HAIRY;), BURKITT LYMPHOMA; and other malignancies.

Descriptor ID	D004854
MeSH Number(s)	B04.280.210.400.500.450 B04.280.382.400.500.400 B04.613.204.500.500.400
Concept/Terms	Herpesvirus 4, Human Herpesvirus 4, Human Burkitt Lymphoma Virus Lymphoma Virus, Burkitt Burkitt's Lymphoma Virus Burkitts Lymphoma Virus E-B Virus E B Virus E-B Viruses Infectious Mononucleosis Virus Infectious Mononucleosis Viruses Mononucleosis Virus, Infectious Mononucleosis Viruses, Infectious Epstein-Barr Virus Epstein Barr Virus Herpesvirus 4 (gamma), Human HHV-4 Human Herpesvirus 4 Burkitt Herpesvirus Herpesvirus, Burkitt EBV

Below are MeSH descriptors whose meaning is more general than "Herpesvirus 4, Human".

Organisms [B]
Viruses [B04]
DNA Viruses [B04.280]
DNA Tumor Viruses [B04.280.210]
Gammaherpesvirinae [B04.280.210.400]
Lymphocryptovirus [B04.280.210.400.500]
Herpesvirus 4, Human [B04.280.210.400.500.450]
Herpesviridae [B04.280.382]
Gammaherpesvirinae [B04.280.382.400]
Lymphocryptovirus [B04.280.382.400.500]
Herpesvirus 4, Human [B04.280.382.400.500.400]
Oncogenic Viruses [B04.613]
DNA Tumor Viruses [B04.613.204]
Gammaherpesvirinae [B04.613.204.500]
Lymphocryptovirus [B04.613.204.500.500]
Herpesvirus 4, Human [B04.613.204.500.500.400]

Below are MeSH descriptors whose meaning is related to "Herpesvirus 4, Human".

Below are MeSH descriptors whose meaning is more specific than "Herpesvirus 4, Human".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Herpesvirus 4, Human" by people in this website by year, and whether "Herpesvirus 4, Human" was a major or minor topic of these publications.

Bar chart showing 28 publications over 19 distinct years, with a maximum of 3 publications in 2006 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	0	1
2001	2	0	2
2004	0	2	2
2005	1	0	1
2006	3	0	3
2007	0	1	1
2008	0	1	1
2009	1	0	1
2010	1	2	3
2011	0	2	2
2012	0	2	2
2014	0	1	1
2016	0	1	1
2017	1	0	1
2018	1	0	1
2019	2	0	2
2020	0	1	1
2021	1	0	1

Below are the most recent publications written about "Herpesvirus 4, Human" by people in Profiles.

Laurynenka V, Ding L, Kaufman KM, James JA, Harley JB. A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies. Front Immunol. 2022; 13:830993.

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Fechtner S, Berens H, Bemis E, Johnson RL, Guthridge CJ, Carlson NE, Demoruelle MK, Harley JB, Edison JD, Norris JA, Robinson WH, Deane KD, James JA, Holers VM. Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles. Arthritis Rheumatol. 2022 04; 74(4):597-603.

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Kashyap D, Baral B, Jakhmola S, Singh AK, Jha HC. Helicobacter pylori and Epstein-Barr Virus Coinfection Stimulates Aggressiveness in Gastric Cancer through the Regulation of Gankyrin. mSphere. 2021 10 27; 6(5):e0075121.

View in: PubMed
Jog NR, James JA. Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. Front Immunol. 2020; 11:623944.

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Jog NR, McClain MT, Heinlen LD, Gross T, Towner R, Guthridge JM, Axtell RC, Pardo G, Harley JB, James JA. Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model. J Autoimmun. 2020 01; 106:102332.

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Jog NR, Young KA, Munroe ME, Harmon MT, Guthridge JM, Kelly JA, Kamen DL, Gilkeson GS, Weisman MH, Karp DR, Gaffney PM, Harley JB, Wallace DJ, Norris JM, James JA. Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals. Ann Rheum Dis. 2019 09; 78(9):1235-1241.

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Jog NR, Chakravarty EF, Guthridge JM, James JA. Epstein Barr Virus Interleukin 10 Suppresses Anti-inflammatory Phenotype in Human Monocytes. Front Immunol. 2018; 9:2198.

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Langer-Gould A, Wu J, Lucas R, Smith J, Gonzales E, Amezcua L, Haraszti S, Chen LH, Quach H, James JA, Barcellos LF, Xiang AH. Epstein-Barr virus, cytomegalovirus, and multiple sclerosis susceptibility: A multiethnic study. Neurology. 2017 Sep 26; 89(13):1330-1337.

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Smith K, Shah H, Muther JJ, Duke AL, Haley K, James JA. Antigen nature and complexity influence human antibody light chain usage and specificity. Vaccine. 2016 05 27; 34(25):2813-20.

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Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18; 83(21):1923-9.

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