"Histamine H1 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Descriptor ID |
D006634
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MeSH Number(s) |
D27.505.519.625.375.425.400 D27.505.696.577.375.425.400
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Concept/Terms |
Histamine H1 Antagonists- Histamine H1 Antagonists
- H1 Antagonists, Histamine
- Antagonists, Histamine H1 Receptor
- Antihistaminics, H1
- H1 Antihistaminics
- Receptor Blockaders, H1
- H1 Receptor Blockaders
- Histamine H1 Blockers
- Histamine H1 Receptor Antagonists
- Histamine H1 Receptor Blockaders
- Antagonists, Histamine H1
- Blockaders, Histamine H1 Receptor
Antihistamines, Classical- Antihistamines, Classical
- Classical Antihistamines
- Antihistaminics, Classical
- Classical Antihistaminics
- First Generation H1 Antagonists
- Antihistamines, Sedating
- Sedating Antihistamines
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Below are MeSH descriptors whose meaning is more general than "Histamine H1 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H1 Antagonists".
This graph shows the total number of publications written about "Histamine H1 Antagonists" by people in this website by year, and whether "Histamine H1 Antagonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histamine H1 Antagonists" by people in Profiles.
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Promethazine-induced psychosis in a 16-year-old girl. Psychosomatics. 2004 Jan-Feb; 45(1):89-90.
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A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis. J Urol. 2003 Sep; 170(3):810-5.
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Management of opioid-induced gastrointestinal effects in patients receiving palliative care. Pharmacotherapy. 2002 Feb; 22(2):240-50.
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Lichenoid and subacute cutaneous lupus erythematosus-like dermatitis associated with antihistamine therapy. J Cutan Pathol. 1999 Feb; 26(2):95-9.