"Cardiomegaly" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Descriptor ID |
D006332
|
| MeSH Number(s) |
C14.280.195 C23.300.775.250
|
| Concept/Terms |
Cardiomegaly- Cardiomegaly
- Heart Enlargement
- Enlargement, Heart
- Enlarged Heart
- Heart, Enlarged
|
Below are MeSH descriptors whose meaning is more general than "Cardiomegaly".
Below are MeSH descriptors whose meaning is more specific than "Cardiomegaly".
This graph shows the total number of publications written about "Cardiomegaly" by people in this website by year, and whether "Cardiomegaly" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 3 | 0 | 3 |
| 2000 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cardiomegaly" by people in Profiles.
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In Vivo Cardiac-specific Expression of Adenylyl Cyclase 4 Gene Protects against Klotho Deficiency-induced Heart Failure. Transl Res. 2022 06; 244:101-113.
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Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis. Am J Physiol Heart Circ Physiol. 2017 Mar 01; 312(3):H375-H383.
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Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice. J Hematol Oncol. 2014 Mar 19; 7:25.
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TRPC1 channels are critical for hypertrophic signaling in the heart. Circ Res. 2009 Nov 06; 105(10):1023-30.
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N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats. Cardiovasc Res. 2007 Mar 01; 73(4):770-82.
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Left atrial diameter as an independent predictor of first clinical cardiovascular events in middle-aged and elderly adults: the Strong Heart Study (SHS). Am Heart J. 2006 Feb; 151(2):412-8.
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Premature death and age-related cardiac dysfunction in male eNOS-knockout mice. J Mol Cell Cardiol. 2004 Sep; 37(3):671-80.
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Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF. FEBS Lett. 2003 Jul 31; 548(1-3):79-84.
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Sprint training normalizes Ca(2+) transients and SR function in postinfarction rat myocytes. J Appl Physiol (1985). 2000 Jul; 89(1):38-46.
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Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8750-5.