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Michael Joseph O'Dwyer

TitleAsst,Grad Research/Allied Hlth
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentRehabilitation Sciences
AddressAHB 3092
1200 N Stonewall Ave
Oklahoma City OK 73117
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Torrance HD, Zhang P, Longbottom ER, Mi Y, Whalley JP, Allcock A, Kwok AJ, Cano-Gamez E, Geoghegan CG, Burnham KL, Antcliffe DB, Davenport EE, Pearse RM, O'Dwyer MJ, Hinds CJ, Knight JC, Gordon AC. A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery. Ann Surg. 2023 Jul 27. PMID: 37497667.
      Citations:    Fields:    Translation:HumansCells
    2. Naicker SD, Feerick CL, Lynch K, Swan D, McEllistrim C, Henderson R, Leonard NA, Treacy O, Natoni A, Rigalou A, Cabral J, Chiu C, Sasser K, Ritter T, O'Dwyer M, Ryan AE. Cyclophosphamide alters the tumor cell secretome to potentiate the anti-myeloma activity of daratumumab through augmentation of macrophage-mediated antibody dependent cellular phagocytosis. Oncoimmunology. 2021 01 25; 10(1):1859263. PMID: 33552684; PMCID: PMC7849715.
      Citations: 7     Fields:    Translation:HumansCells
    3. Fogarty H, Dowling A, O'Brien D, Langabeer S, Bacon CL, Flavin R, O'Dwyer M, Hennessy B, O'Leary H, Crotty G, Henderson R, Nolan J, Thornton P, Vandenberghe E, Quinn F. Biclonal lymphoproliferative disorders: another association with NOTCH1-mutated chronic lymphocytic leukaemias. Ir J Med Sci. 2021 Aug; 190(3):1087-1094. PMID: 33068240.
      Citations:    Fields:    Translation:Humans
    4. Zhang D, Guo R, Lei L, Liu H, Wang Y, Wang Y, Qian H, Dai T, Zhang T, Lai Y, Wang J, Liu Z, Chen T, He A, O'Dwyer M, Hu J. Frontline Science: COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes. J Leukoc Biol. 2021 01; 109(1):13-22. PMID: 33040384; PMCID: PMC7675546.
      Citations: 162     Fields:    Translation:HumansCells
    5. O'Dwyer J, O'Cearbhaill RE, Wylie R, O'Mahony S, O'Dwyer M, Duffy GP, Dolan EB. Enhancing delivery of small molecule and cell-based therapies for ovarian cancer using advanced delivery strategies. Adv Ther (Weinh). 2020 Nov; 3(11). PMID: 33709016; PMCID: PMC7942751.
      Citations: 1     
    6. Kielty J, Duggan WP, O'Dwyer M. Extensive pneumatosis intestinalis and portal venous gas mimicking mesenteric ischaemia in a patient with SARS-CoV-2. Ann R Coll Surg Engl. 2020 Jul; 102(6):e145-e147. PMID: 32538098; PMCID: PMC7388941.
      Citations: 14     Fields:    Translation:HumansCellsPHPublic Health
    7. Bond L, Carroll R, Mulryan N, O'Dwyer M, O'Connell J, Monaghan R, Sheerin F, McCallion P, McCarron M. Biopsychosocial factors associated with depression and anxiety in older adults with intellectual disability: results of the wave 3 Intellectual Disability Supplement to The Irish Longitudinal Study on Ageing. J Intellect Disabil Res. 2020 05; 64(5):368-380. PMID: 32215976.
      Citations: 4     Fields:    Translation:Humans
    8. Langabeer SE, Faryal R, O'Dwyer M, Loingsigh SN. Patient-Initiated Discontinuation of Tyrosine Kinase Inhibitor for Chronic Myeloid Leukemia. Case Rep Hematol. 2020; 2020:9571691. PMID: 32274226; PMCID: PMC7125505.
    9. Waller K, James C, de Jong A, Blackmore L, Ma Y, Stagg A, Kelsell D, O'Dwyer M, Hutchins R, Alazawi W. ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis. Front Immunol. 2019; 10:1902. PMID: 31507587; PMCID: PMC6718469.
      Citations: 7     Fields:    Translation:HumansCells
    10. Coutre SE, Byrd JC, Hillmen P, Barrientos JC, Barr PM, Devereux S, Robak T, Kipps TJ, Schuh A, Moreno C, Furman RR, Burger JA, O'Dwyer M, Ghia P, Valentino R, Chang S, Dean JP, James DF, O'Brien SM. Long-term safety of single-agent ibrutinib in patients with chronic lymphocytic leukemia in 3 pivotal studies. Blood Adv. 2019 06 25; 3(12):1799-1807. PMID: 31196847; PMCID: PMC6595265.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    11. Facon T, Kumar S, Plesner T, Orlowski RZ, Moreau P, Bahlis N, Basu S, Nahi H, Hulin C, Quach H, Goldschmidt H, O'Dwyer M, Perrot A, Venner CP, Weisel K, Mace JR, Raje N, Attal M, Tiab M, Macro M, Frenzel L, Leleu X, Ahmadi T, Chiu C, Wang J, Van Rampelbergh R, Uhlar CM, Kobos R, Qi M, Usmani SZ, MAIA Trial Investigators. Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma. N Engl J Med. 2019 05 30; 380(22):2104-2115. PMID: 31141632; PMCID: PMC10045721.
      Citations: 326     Fields:    Translation:HumansCTClinical Trials
    12. Bond L, Carroll R, Mulryan N, O'Dwyer M, O'Connell J, Monaghan R, Sheerin F, McCallion P, McCarron M. The association of life events and mental ill health in older adults with intellectual disability: results of the wave 3 Intellectual Disability Supplement to The Irish Longitudinal Study on Ageing. J Intellect Disabil Res. 2019 05; 63(5):454-465. PMID: 30697858.
      Citations: 10     Fields:    Translation:Humans
    13. Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB, O'Dwyer M, Nourshargh S, Pennington DJ, Barnes MR, Brohi K. Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med. 2018 10; 15(10):e1002694. PMID: 30379817; PMCID: PMC6209129.
      Citations: 2     Fields:    
    14. Torrance HDT, Longbottom ER, Vivian ME, Lalabekyan B, Abbott TEF, Ackland GL, Hinds CJ, Pearse RM, O'Dwyer MJ. Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. PLoS One. 2018; 13(9):e0203795. PMID: 30212506; PMCID: PMC6136775.
      Citations: 13     Fields:    Translation:HumansCells
    15. Jones TF, Bekele S, O'Dwyer MJ, Prowle JR. MicroRNAs in Acute Kidney Injury. Nephron. 2018; 140(2):124-128. PMID: 29870986.
      Citations: 14     Fields:    Translation:Humans
    16. Haines RW, Lin SP, Hewson R, Kirwan CJ, Torrance HD, O'Dwyer MJ, West A, Brohi K, Pearse RM, Zolfaghari P, Prowle JR. Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model. Sci Rep. 2018 02 26; 8(1):3665. PMID: 29483607; PMCID: PMC5827665.
      Citations: 20     Fields:    Translation:Humans
    17. O'Dwyer M, Peklar J, Mulryan N, McCallion P, McCarron M, Henman MC. Prevalence and patterns of anti-epileptic medication prescribing in the treatment of epilepsy in older adults with intellectual disabilities. J Intellect Disabil Res. 2018 03; 62(3):245-261. PMID: 29314463.
      Citations: 4     Fields:    Translation:Humans
    18. Appleby N, O'Brien D, Quinn FM, Smyth L, Kelly J, Parker I, Scott K, Cahill MR, Crotty G, Enright H, Hennessy B, Hodgson A, Leahy M, O'Leary H, O'Dwyer M, Hayat A, Vandenberghe EA. Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL. Leuk Lymphoma. 2018 06; 59(6):1338-1347. PMID: 28925785.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    19. Asehnoune K, Balogh Z, Citerio G, Cap A, Billiar T, Stocchetti N, Cohen MJ, Pelosi P, Curry N, Gaarder C, Gruen R, Holcomb J, Hunt BJ, Juffermans NP, Maegele M, Midwinter M, Moore FA, O'Dwyer M, Pittet JF, Sch?chl H, Schreiber M, Spinella PC, Stanworth S, Winfield R, Brohi K. The research agenda for trauma critical care. Intensive Care Med. 2017 Sep; 43(9):1340-1351. PMID: 28756471.
      Citations: 21     Fields:    Translation:Humans
    20. Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB, O'Dwyer M, Nourshargh S, Pennington DJ, Barnes MR, Brohi K. Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med. 2017 Jul; 14(7):e1002352. PMID: 28715416; PMCID: PMC5513400.
      Citations: 43     Fields:    Translation:HumansCells
    21. O'Dwyer M, Peklar J, Mulryan N, McCallion P, McCarron M, Henman MC. Prevalence, patterns and factors associated with psychotropic use in older adults with intellectual disabilities in Ireland. J Intellect Disabil Res. 2017 10; 61(10):969-983. PMID: 28639298.
      Citations: 9     Fields:    Translation:Humans
    22. O'Dwyer MJ, Starczewska MH, Schrenzel J, Zacharowski K, Ecker DJ, Sampath R, Brealey D, Singer M, Libert N, Wilks M, Vincent JL. The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis-a prospective multi-centre European observational study. Clin Microbiol Infect. 2017 Mar; 23(3):208.e1-208.e6. PMID: 27890455.
      Citations: 10     Fields:    Translation:HumansCells
    23. Wallace T, Gibbons D, O'Dwyer M, Curran TP. International evolution of fat, oil and grease (FOG) waste management - A review. J Environ Manage. 2017 Feb 01; 187:424-435. PMID: 27838205.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    24. Longbottom ER, Torrance HD, Owen HC, Fragkou PC, Hinds CJ, Pearse RM, O'Dwyer MJ. Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways. Ann Surg. 2016 08; 264(2):370-7. PMID: 26445474.
      Citations: 37     Fields:    Translation:Humans
    25. Torrance HD, Pearse RM, O'Dwyer MJ. Does major surgery induce immune suppression and increase the risk of postoperative infection? Curr Opin Anaesthesiol. 2016 Jun; 29(3):376-83. PMID: 26963469.
      Citations: 20     Fields:    Translation:Humans
    26. Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance HD, Owen HC, O'Dwyer MJ, O'Brien A, Stagg AJ, Bhattacharya S, Foster GR, Alazawi W. Systemic Inflammatory Response Syndrome After Major Abdominal Surgery Predicted by Early Upregulation of TLR4 and TLR5. Ann Surg. 2016 May; 263(5):1028-37. PMID: 26020106.
      Citations: 23     Fields:    Translation:HumansCells
    27. Burger JA, Tedeschi A, Barr PM, Robak T, Owen C, Ghia P, Bairey O, Hillmen P, Bartlett NL, Li J, Simpson D, Grosicki S, Devereux S, McCarthy H, Coutre S, Quach H, Gaidano G, Maslyak Z, Stevens DA, Janssens A, Offner F, Mayer J, O'Dwyer M, Hellmann A, Schuh A, Siddiqi T, Polliack A, Tam CS, Suri D, Cheng M, Clow F, Styles L, James DF, Kipps TJ, RESONATE-2 Investigators. Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia. N Engl J Med. 2015 Dec 17; 373(25):2425-37. PMID: 26639149; PMCID: PMC4722809.
      Citations: 579     Fields:    Translation:HumansCTClinical Trials
    28. Owen HC, Torrance HD, Jones TF, Pearse RM, Hinds CJ, Brohi K, O'Dwyer MJ. Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma. J Trauma Acute Care Surg. 2015 Nov; 79(5):766-72. PMID: 26496100.
      Citations: 5     Fields:    Translation:HumansCells
    29. Vincent JL, Brealey D, Libert N, Abidi NE, O'Dwyer M, Zacharowski K, Mikaszewska-Sokolewicz M, Schrenzel J, Simon F, Wilks M, Picard-Maureau M, Chalfin DB, Ecker DJ, Sampath R, Singer M, Rapid Diagnosis of Infections in the Critically Ill Team. Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections. Crit Care Med. 2015 Nov; 43(11):2283-91. PMID: 26327198; PMCID: PMC4603364.
      Citations: 71     Fields:    Translation:HumansCells
    30. O'Dwyer MJ, Owen HC, Torrance HD. The perioperative immune response. Curr Opin Crit Care. 2015 Aug; 21(4):336-42. PMID: 26103142.
      Citations: 26     Fields:    Translation:Humans
    31. Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ. Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Ann Surg. 2015 Apr; 261(4):751-9. PMID: 24670848.
      Citations: 20     Fields:    Translation:HumansCells
    32. Torrance HD, Vivian ME, Brohi K, Prowle JR, Pearse RM, Owen HC, Hinds CJ, O'Dwyer MJ. Changes in gene expression following trauma are related to the age of transfused packed red blood cells. J Trauma Acute Care Surg. 2015 Mar; 78(3):535-42. PMID: 25710424.
      Citations: 7     Fields:    Translation:Humans
    33. Fragkou PC, Torrance HD, Pearse RM, Ackland GL, Prowle JR, Owen HC, Hinds CJ, O'Dwyer MJ. Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. Crit Care. 2014 Oct 01; 18(5):541. PMID: 25270110; PMCID: PMC4201915.
      Citations: 13     Fields:    Translation:HumansCells
    34. Giles FJ, Krawczyk J, O'Dwyer M, Swords R, Freeman C. The role of inflammation in leukaemia. Adv Exp Med Biol. 2014; 816:335-60. PMID: 24818729.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    35. Vincenz L, J?ger R, O'Dwyer M, Samali A. Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma. Mol Cancer Ther. 2013 Jun; 12(6):831-43. PMID: 23729400.
      Citations: 76     Fields:    Translation:HumansCells
    36. McMorrow RC, Windsor JS, Hart ND, Richards P, Rodway GW, Ahuja VY, O'Dwyer MJ, Mythen MG, Grocott MP, Caudwell Xtreme Everest Research Group. Closed and open breathing circuit function in healthy volunteers during exercise at Mount Everest base camp (5300 m). Anaesthesia. 2012 Aug; 67(8):875-80. PMID: 22519895.
      Citations:    Fields:    Translation:Humans
    37. White M, Martin-Loeches I, Lawless MW, O'Dwyer MJ, Doherty DG, Young V, Kelleher D, McManus R, Ryan T. Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression. Chest. 2011 Mar; 139(3):626-632. PMID: 20829336.
      Citations: 10     Fields:    Translation:Humans
    38. White M, Lawless MW, O'Dwyer MJ, Grealy R, Connell BO, Stordeur P, Kelleher D, McManus R, Ryan T. Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection. Cytokine. 2010 Jun; 50(3):322-7. PMID: 20207161.
      Citations: 8     Fields:    Translation:HumansCells
    39. Swords RT, Kelly KR, Smith PG, Garnsey JJ, Mahalingam D, Medina E, Oberheu K, Padmanabhan S, O'Dwyer M, Nawrocki ST, Giles FJ, Carew JS. Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia. Blood. 2010 May 06; 115(18):3796-800. PMID: 20203261.
      Citations: 151     Fields:    Translation:HumansAnimalsCells
    40. Windsor JS, Hamilton E, Grocott MP, O'Dwyer MJ, Milledge JS. The Snow Snorkel: a proof of concept study. Wilderness Environ Med. 2009; 20(1):61-5. PMID: 19364164.
      Citations: 2     Fields:    Translation:Humans
    41. O'Dwyer MJ, Mankan AK, Ryan AW, Lawless MW, Stordeur P, Kelleher D, McManus R, Ryan T. Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis. Int J Immunogenet. 2008 Aug; 35(4-5):279-85. PMID: 18643840.
      Citations: 3     Fields:    Translation:Humans
    42. White M, Mankan A, Lawless MW, O'Dwyer MJ, McManus R, Ryan T. Mortality in humans with pneumonia and sepsis is related to an uncompensated anti-inflammatory response to infection. Arch Intern Med. 2008 Jul 14; 168(13):1468-9; author reply 1469. PMID: 18625929.
      Citations: 4     Fields:    Translation:HumansAnimals
    43. O'Dwyer MJ, Mankan AK, White M, Lawless MW, Stordeur P, O'Connell B, Kelleher DP, McManus R, Ryan T. The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression. Intensive Care Med. 2008 Apr; 34(4):683-91. PMID: 18227999.
      Citations: 13     Fields:    Translation:Humans
    44. O'Dwyer MJ, Mahon N, McCarthy J, Colreavey F. The presentation of an aortic root abscess as an acute coronary syndrome. J Cardiothorac Vasc Anesth. 2008 Jun; 22(3):446-8. PMID: 18503939.
      Citations: 1     Fields:    Translation:Humans
    45. Lawless MW, White M, Mankan AK, O'Dwyer MJ, Norris S. Elevated MCP-1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis. Tissue Antigens. 2007 Oct; 70(4):294-300. PMID: 17767550.
      Citations: 6     Fields:    Translation:Humans
    46. Lawless MW, Mankan AK, White M, O'Dwyer MJ, Norris S. Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses. BMC Cell Biol. 2007 Jul 24; 8:30. PMID: 17650303; PMCID: PMC1947972.
      Citations: 14     Fields:    Translation:HumansCells
    47. Duggan E, O'Dwyer MJ, Caraher E, Diviney D, McGovern E, Kelleher D, McManus R, Ryan T. Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism. Anesth Analg. 2007 Jun; 104(6):1343-7, table of contents. PMID: 17513622.
      Citations: 7     Fields:    Translation:Humans
    48. O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T. The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression. Shock. 2006 Dec; 26(6):544-50. PMID: 17117127.
      Citations: 15     Fields:    Translation:Humans
    49. Ryan R, Thornton J, Duggan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T. Gene polymorphism and requirement for vasopressor infusion after cardiac surgery. Ann Thorac Surg. 2006 Sep; 82(3):895-901. PMID: 16928504.
      Citations: 6     Fields:    Translation:Humans
    50. Duggan E, Caraher E, Gately K, O'Dwyer M, McGovern E, Kelleher D, McManus R, Ryan T. Tumor necrosis factor-alpha and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery. Crit Care Med. 2006 Aug; 34(8):2134-9. PMID: 16763510.
      Citations: 9     Fields:    Translation:HumansCells
    51. O'Dwyer MJ, Duggan E, Ryan T. Letter regarding article by Tomic et al, "transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting". Circulation. 2006 May 16; 113(19):e765; author reply e766. PMID: 16702480.
      Citations:    Fields:    Translation:HumansCells
    52. O'Dwyer MJ, Dempsey F, Crowley V, Kelleher DP, McManus R, Ryan T. Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study. Crit Care. 2006; 10(5):R139. PMID: 17002794; PMCID: PMC1751072.
      Citations: 43     Fields:    Translation:Humans
    53. Rathbun RK, Christianson TA, Faulkner GR, Jones G, Keeble W, O'Dwyer M, Bagby GC. Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members. Blood. 2000 Dec 15; 96(13):4204-11. PMID: 11110692.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    54. Bell JN, Reen D, O'Dwyer M. Clinical application of the I.B.M. cell separator. Ir Med J. 1975 Sep 13; 68(17):407-11. PMID: 1057536.
      Citations:    Fields:    Translation:HumansCells
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