"Lipofuscin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently increases in quantity with age.
Descriptor ID |
D008062
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MeSH Number(s) |
D10.460 D23.767.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipofuscin".
Below are MeSH descriptors whose meaning is more specific than "Lipofuscin".
This graph shows the total number of publications written about "Lipofuscin" by people in this website by year, and whether "Lipofuscin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipofuscin" by people in Profiles.
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Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):13094-13104.
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A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis. Invest Ophthalmol Vis Sci. 2013 Jan 07; 54(1):85-95.
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DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice. J Clin Invest. 2012 Sep; 122(9):3221-6.
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Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. Biochim Biophys Acta. 2012 Jul; 1822(7):1169-79.
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Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells. Free Radic Biol Med. 2001 Jul 15; 31(2):256-65.
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Clinicopathological problems of the local tissue effect of copper-containing IUDs. II. Electron-microscopic study of the endometrial scraping. Acta Chir Hung. 1989; 30(2):133-8.