"Keratins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
| Descriptor ID |
D007633
|
| MeSH Number(s) |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratins".
Below are MeSH descriptors whose meaning is more specific than "Keratins".
This graph shows the total number of publications written about "Keratins" by people in this website by year, and whether "Keratins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Keratins" by people in Profiles.
-
Artifacts and Common Errors in Protein Gel Electrophoresis. Methods Mol Biol. 2019; 1855:511-518.
-
Lymphoepithelioma-like carcinoma of the ureter: a rare presentation, synchronous with conventional urothelial carcinoma. Can J Urol. 2017 Feb; 24(1):8673-8675.
-
Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines. J Neurosurg Spine. 2014 Sep; 21(3):386-93.
-
Sinonasal non-keratinizing squamous cell carcinoma with nasal skin extension as the initial presentation. J Cutan Pathol. 2012 Aug; 39(8):791-4.
-
Common artifacts and mistakes made in electrophoresis. Methods Mol Biol. 2012; 869:633-40.
-
The effects of water and microstructure on the mechanical properties of bighorn sheep (Ovis canadensis) horn keratin. Acta Biomater. 2011 Mar; 7(3):1228-40.
-
Cytokeratin profiles of male breast cancers. Histopathology. 2006 Oct; 49(4):365-70.
-
Breast cancer pseudometastasis in a sentinel lymph node with cytokeratin-positive debris. Breast J. 2005 Mar-Apr; 11(2):134-7.
-
Foetal rat lung epithelial (FRLE) cells: partial characterisation and response to pneumotoxins. Toxicol In Vitro. 2004 Feb; 18(1):79-88.
-
Regulation and role of interleukin 6 in wounded human epithelial keratinocytes. Cytokine. 2001 Sep 21; 15(6):328-36.