"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
| Descriptor ID |
D007656
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| MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
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Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell. Sci Rep. 2022 11 16; 12(1):19657.
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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13787-92.
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The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium. J Biol Chem. 2012 Jul 20; 287(30):25098-110.
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Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction. Arch Biochem Biophys. 2011 Oct; 514(1-2):8-15.
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Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus. J Biol Chem. 2011 Aug 19; 286(33):29428-29439.
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Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma. Hum Mol Genet. 2007 Dec 15; 16(24):3136-48.
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Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct 03; 45(39):12136-43.
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Urinary organic anion excretion in response to dietary acid and base loading. J Am Soc Nephrol. 1995 Feb; 5(8):1624-9.
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pH studies toward the elucidation of the auxiliary catalyst for pig heart aspartate aminotransferase. Biochemistry. 1983 Jan 18; 22(2):375-82.