Glucose-6-Phosphate Isomerase
"Glucose-6-Phosphate Isomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
| Descriptor ID |
D005956
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| MeSH Number(s) |
D08.811.399.475.200.350
|
| Concept/Terms |
Glucose-6-Phosphate Isomerase- Glucose-6-Phosphate Isomerase
- Glucose 6 Phosphate Isomerase
- Isomerase, Glucose-6-Phosphate
- Isomerase, Glucose 6 Phosphate
- Phosphohexose Isomerase
- Isomerase, Phosphohexose
- Glucosephosphate Isomerase
- Isomerase, Glucosephosphate
- Phosphoglucose Isomerase
- Isomerase, Phosphoglucose
Autocrine Motility Factor- Autocrine Motility Factor
- Motility Factor, Autocrine
- Tumor Autocrine Motility Factor
- Tumor-Cell Autocrine Motility Factor
- Tumor Cell Autocrine Motility Factor
- Neuroleukin
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This graph shows the total number of publications written about "Glucose-6-Phosphate Isomerase" by people in this website by year, and whether "Glucose-6-Phosphate Isomerase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
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Below are the most recent publications written about "Glucose-6-Phosphate Isomerase" by people in Profiles.
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Long-term changes in metapopulation genetic structure: a quarter-century retrospective study on low-Arctic rock pool Daphnia. Proc Biol Sci. 2010 Jan 07; 277(1678):139-46.
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Genetically-based trade-offs in response to stoichiometric food quality influence competition in a keystone aquatic herbivore. Ecol Lett. 2009 Nov; 12(11):1229-37.
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Nuclear gene genealogies reveal historical, demographic and selective factors associated with speciation in field crickets. Genetics. 2003 Apr; 163(4):1389-401.
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Cutaneous leishmaniasis: iso-enzyme characterisation of Leishmania tropica. J Pak Med Assoc. 1997 Nov; 47(11):270-3.
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Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase. Arch Biochem Biophys. 1988 May 15; 263(1):96-106.