"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 4 | 5 |
| 1996 | 2 | 1 | 3 |
| 1997 | 1 | 4 | 5 |
| 1999 | 2 | 5 | 7 |
| 2000 | 4 | 2 | 6 |
| 2001 | 1 | 2 | 3 |
| 2002 | 3 | 5 | 8 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 5 | 6 |
| 2006 | 1 | 1 | 2 |
| 2007 | 3 | 4 | 7 |
| 2008 | 2 | 4 | 6 |
| 2009 | 3 | 6 | 9 |
| 2010 | 2 | 3 | 5 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 6 | 8 |
| 2014 | 0 | 5 | 5 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 6 | 8 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 6 | 7 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. J Clin Invest. 2025 Mar 17; 135(6).
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Polyomavirus BK-Specific CD4+ T Cells Response to VP1 Stimulation in Kidney Transplant Recipients. Iran J Allergy Asthma Immunol. 2024 May 27; 23(3):272-287.
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Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation. Commun Biol. 2024 Feb 24; 7(1):228.
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The Polyamine Putrescine Is a Positive Regulator of Group 3 Innate Lymphocyte Activation. Immunohorizons. 2023 01 01; 7(1):41-48.
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Use of a Clostridioides difficile Murine Immunization and Challenge Model to Evaluate Single and Combination Vaccine Adjuvants Consisting of Alum and NKT Cell-Activating Ligands. Front Immunol. 2021; 12:818734.
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a-Galactosylceramide-Reactive NKT Cells Increase IgG1 Class Switch against a Clostridioides difficile Polysaccharide Antigen and Enhance Immunity against a Live Pathogen Challenge. Infect Immun. 2021 10 15; 89(11):e0043821.
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Targeting human langerin promotes HIV-1 specific humoral immune responses. PLoS Pathog. 2021 07; 17(7):e1009749.
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Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-? protection to influenza virus in mouse. Respir Res. 2021 Apr 20; 22(1):112.
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Overlapping B cell pathways in severe COVID-19 and lupus. Nat Immunol. 2020 12; 21(12):1478-1480.
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Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype. J Allergy Clin Immunol. 2020 12; 146(6):1419-1433.