"Manganese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Below are MeSH descriptors whose meaning is more general than "Manganese".
Below are MeSH descriptors whose meaning is more specific than "Manganese".
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Below are the most recent publications written about "Manganese" by people in Profiles.
RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a. Cell Rep. 2017 12 26; 21(13):3728-3739.
Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes. Antimicrob Agents Chemother. 2016 09; 60(9):5331-6.
Nitrite reduction by Co(II) and Mn(II) substituted myoglobins: towards understanding necessary components of Mb nitrite reductase activity. J Inorg Biochem. 2012 Feb; 107(1):47-53.
A synthetic model of the Mn3Ca subsite of the oxygen-evolving complex in photosystem II. Science. 2011 Aug 05; 333(6043):733-6.
Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations. J Inorg Biochem. 2008 Feb; 102(2):216-33.
An isothermal titration calorimetry study of the binding of substrates and ligands to the tartrate dehydrogenase from Pseudomonas putida reveals half-of-the-sites reactivity. Biochemistry. 2006 Jul 25; 45(29):9000-6.
Fiber-optic infrared spectroelectrochemical studies of six-coordinate manganese nitrosyl porphyrins in nonaqueous media. Inorg Chem. 2006 Mar 20; 45(6):2661-8.
Alterations in human trabecular meshwork cell homeostasis by selenium. Exp Eye Res. 2006 Apr; 82(4):637-47.
Synthesis, characterization and molecular structures of six-coordinate manganese nitrosyl porphyrins. Dalton Trans. 2004 Jan 07; (1):44-50.
Competitive binding of triplex-forming oligonucleotides in the two alternate promoters of the PMP22 gene. Antisense Nucleic Acid Drug Dev. 2001 Aug; 11(4):233-46.