"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
| Descriptor ID |
D007928
|
| MeSH Number(s) |
E05.940.402 G07.225.500 G07.690.773.875.750 G07.690.936.500.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Radioprotective properties of tocopherol succinate against ionizing radiation in mice. J Radiat Res. 2013 Mar 01; 54(2):210-20.
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Anthrax lethal toxin-induced gene expression changes in mouse lung. Toxins (Basel). 2011 09; 3(9):1111-30.
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Whole body protection to lethally irradiated mice by oral administration of semipurified fraction of Podophyllum hexandrum and post irradiation treatment of Picrorhiza kurroa. Tokai J Exp Clin Med. 2008 Apr 20; 33(1):6-12.
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Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii. FEMS Microbiol Lett. 2006 Jun; 259(2):295-302.
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Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench. Phytomedicine. 2002 Apr; 9(3):249-53.
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Pretreatment with troglitazone decreases lethality during endotoxemia in mice. J Endotoxin Res. 2002; 8(4):307-14.
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The acute and subchronic toxicity of BRB-I-28, a novel class Ib antiarrhythmic agent, in CD-1 mice. Food Chem Toxicol. 2000 Sep; 38(9):817-23.
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Preliminary acute and subchronic toxicity studies of GLG-V-13, a novel class III antiarrhythmic agent, in mice. Arzneimittelforschung. 2000 Jan; 50(1):31-8.
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Effects of ricin on the ability of rabbit arteries to contract and relax. J Appl Toxicol. 1995 Jan-Feb; 15(1):37-43.
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The cardiovascular effects of ricin in rabbits. Pharmacol Toxicol. 1994 Mar; 74(3):148-52.