"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
| Descriptor ID |
D009435
|
| MeSH Number(s) |
G02.111.820.850 G04.835.850 G07.265.880 G11.561.830
|
| Concept/Terms |
Synaptic Transmission- Synaptic Transmission
- Neural Transmission
- Neurotransmission
- Transmission, Neural
- Transmission, Synaptic
|
Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".
Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".
This graph shows the total number of publications written about "Synaptic Transmission" by people in this website by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 3 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2009 | 3 | 1 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 3 | 5 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Synaptic Transmission" by people in Profiles.
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Synapse-Specific Defects in Synaptic Transmission in the Cerebellum of W246G Mutant ELOVL4 Rats-a Model of Human SCA34. J Neurosci. 2023 Aug 16; 43(33):5963-5974.
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A Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission. Cell Death Dis. 2023 Jul 13; 14(7):420.
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Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder. Cell Rep. 2021 11 09; 37(6):109970.
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Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation. JCI Insight. 2019 12 05; 4(23).
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A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine. Addict Biol. 2020 07; 25(4):e12763.
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Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain. Geroscience. 2019 04; 41(2):109-123.
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Neuroligin-2 Determines Inhibitory Synaptic Transmission in the Lateral Septum to Optimize Stress-Induced Neuronal Activation and Avoidance Behavior. Biol Psychiatry. 2019 06 15; 85(12):1046-1055.
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Secreted amyloid-ß precursor protein functions as a GABABR1a ligand to modulate synaptic transmission. Science. 2019 01 11; 363(6423).
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A model for studying the energetics of sustained high frequency firing. PLoS One. 2018; 13(4):e0196508.
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Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome. Mol Cell Neurosci. 2018 04; 88:33-42.