CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
Descriptor ID |
D015496
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MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 2 | 2 |
1999 | 1 | 0 | 1 |
2000 | 1 | 1 | 2 |
2001 | 0 | 1 | 1 |
2002 | 2 | 1 | 3 |
2005 | 2 | 2 | 4 |
2006 | 2 | 2 | 4 |
2007 | 7 | 0 | 7 |
2008 | 3 | 4 | 7 |
2009 | 3 | 2 | 5 |
2010 | 2 | 6 | 8 |
2011 | 3 | 3 | 6 |
2012 | 2 | 0 | 2 |
2013 | 2 | 1 | 3 |
2014 | 3 | 0 | 3 |
2015 | 2 | 1 | 3 |
2016 | 3 | 0 | 3 |
2017 | 1 | 0 | 1 |
2018 | 2 | 1 | 3 |
2019 | 2 | 3 | 5 |
2020 | 0 | 2 | 2 |
2021 | 1 | 1 | 2 |
2022 | 0 | 1 | 1 |
2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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TScan-II: A genome-scale platform for the de novo identification of CD4+ T?cell epitopes. Cell. 2023 Dec 07; 186(25):5569-5586.e21.
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Acetylcholine-producing CD4 T cells regulate vasculature in humans. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2303525120.
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Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell. Sci Rep. 2022 11 16; 12(1):19657.
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Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature. Ann Rheum Dis. 2022 10; 81(10):1428-1437.
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Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8+ T Cell-Dependent Manner. Front Immunol. 2021; 12:742154.
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CD4+?T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities. Sci Rep. 2021 02 17; 11(1):4011.
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T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. Nat Commun. 2020 10 26; 11(1):5406.
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Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells. J Immunol. 2020 11 01; 205(9):2479-2488.
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Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. Brain Behav Immun. 2020 07; 87:795-803.
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Hepatitis C virus-specific CD4+ T cell phenotype and function in different infection outcomes. J Clin Invest. 2020 02 03; 130(2):768-773.