"Receptors, Opioid, mu" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid receptors recognized by its pharmacological profile. Mu opioid receptors bind, in decreasing order of affinity, endorphins, dynorphins, met-enkephalin, and leu-enkephalin. They have also been shown to be molecular receptors for morphine.
| Descriptor ID |
D017450
|
| MeSH Number(s) |
D12.776.543.750.695.620.550 D12.776.543.750.720.600.610.550 D12.776.543.750.750.555.610.550
|
| Concept/Terms |
Receptors, Opioid, mu- Receptors, Opioid, mu
- Opioid Receptors, mu
- mu Opioid Receptors
- Receptors, mu Opioid
- Receptors, mu
- mu Receptor
- Receptor, mu
- mu Receptors
- mu Opioid Receptor
- Opioid Receptor, mu
- Receptor, mu Opioid
Morphine Receptor- Morphine Receptor
- Receptor, Morphine
- Receptors, Morphine
- Morphine Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Opioid, mu".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Opioid [D12.776.543.750.695.620]
- Receptors, Opioid, mu [D12.776.543.750.695.620.550]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Opioid [D12.776.543.750.720.600.610]
- Receptors, Opioid, mu [D12.776.543.750.720.600.610.550]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Opioid [D12.776.543.750.750.555.610]
- Receptors, Opioid, mu [D12.776.543.750.750.555.610.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Opioid, mu".
This graph shows the total number of publications written about "Receptors, Opioid, mu" by people in this website by year, and whether "Receptors, Opioid, mu" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Opioid, mu" by people in Profiles.
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Cortisol Stress Response in Men and Women Modulated Differentially by the Mu-Opioid Receptor Gene Polymorphism OPRM1 A118G. Neuropsychopharmacology. 2015 Oct; 40(11):2546-54.
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A pharmacological comparison of the cloned frog and human mu opioid receptors reveals differences in opioid affinity and function. Eur J Pharmacol. 2008 Dec 03; 599(1-3):36-43.
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Orphanin FQ/nociceptin potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin-Induced mu-opioid receptor phosphorylation. Mol Pharmacol. 2005 Aug; 68(2):447-56.
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Mu-opioid-induced desensitization of opioid receptor-like 1 and mu-opioid receptors: differential intracellular signaling determines receptor sensitivity. J Pharmacol Exp Ther. 2003 Sep; 306(3):965-72.
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Assessing opioid regulation of adenylyl cyclase activity in intact cells. Methods Mol Med. 2003; 84:29-37.
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Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between mu and ORL1 receptors following prolonged agonist exposure. Neuropharmacology. 2002 Nov; 43(6):979-90.
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Orphanin FQ/nociceptin blocks chronic morphine-induced tyrosine hydroxylase upregulation. Brain Res Mol Brain Res. 2002 Sep 30; 105(1-2):38-46.
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Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk. J Pharmacol Exp Ther. 2002 Aug; 302(2):502-9.
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Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity. Alcohol Clin Exp Res. 2002 May; 26(5):688-94.
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beta-Funaltrexamine inactivates ORL1 receptors in BE(2)-C human neuroblastoma cells. Eur J Pharmacol. 2000 Aug 18; 402(1-2):R1-37.