"fas Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
| Descriptor ID |
D019014
|
| MeSH Number(s) |
D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
|
| Concept/Terms |
fas Receptor- fas Receptor
- Receptor, fas
- fas Antigen
- fas Antigens
- APO-1 Antigen
- APO 1 Antigen
- CD95 Antigen
- TNFRSF6 Receptor
- Receptor, TNFRSF6
- Antigens, CD95
- Receptors, fas
- fas Receptors
- Tumor Necrosis Factor Receptor Superfamily, Member 6
- Fas Cell Surface Death Receptor
- CD95 Antigens
|
Below are MeSH descriptors whose meaning is more general than "fas Receptor".
Below are MeSH descriptors whose meaning is more specific than "fas Receptor".
This graph shows the total number of publications written about "fas Receptor" by people in this website by year, and whether "fas Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2014 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "fas Receptor" by people in Profiles.
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Amelioration of ongoing experimental autoimmune encephalomyelitis with fluoxetine. J Neuroimmunol. 2017 12 15; 313:77-81.
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Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study. J Proteome Res. 2016 07 01; 15(7):2102-14.
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Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare. Arthritis Rheumatol. 2014 Jul; 66(7):1888-99.
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Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population. PLoS One. 2014; 9(2):e90264.
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Clinical utility of urinary soluble Fas in screening for bladder cancer. Asia Pac J Clin Oncol. 2016 Jun; 12(2):e215-21.
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Ethanol plus the Jo2 Fas agonistic antibody-induced liver injury is attenuated in mice with partial ablation of argininosuccinate synthase. Alcohol Clin Exp Res. 2014 Mar; 38(3):649-56.
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Caspase-dependent inhibition of store-operated Ca(2+) entry into apoptosis-committed Jurkat cells. Biochem Biophys Res Commun. 2010 Aug 20; 399(2):198-202.
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Modulation of Fas-FasL related apoptosis by PBN in the early phases of choline deficient diet-mediated hepatocarcinogenesis in rats. Free Radic Res. 2007 Sep; 41(9):972-80.
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The role of Fas in the immune system biology of IL-2R alpha knockout mice: interplay among regulatory T cells, inflammation, hemopoiesis, and apoptosis. J Immunol. 2005 Aug 01; 175(3):1965-73.
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Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells. Cancer Res. 2005 Apr 15; 65(8):3017-24.