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A. Darise Farris

TitleAssociate Member
InstitutionOklahoma Medical Research Foundation
DepartmentArthritis and Clinical Immunology
Addressn/a
825 N.E. 13th Street
Oklahoma City OK 73104
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    Collapse research activities and funding
    R21DE029302     (FARRIS, A DARISE)Jul 1, 2020 - Jun 30, 2022
    NIH
    Integrative single cell and spatial transcriptomics of salivary glands in Sjogren's syndrome
    Role: Principal Investigator
    R01AR074310     (FARRIS, A DARISE)Sep 10, 2018 - Jun 30, 2023
    NIH
    Specificity and Molecular Definition of Pathogenic Lymphocytes in Sjogren's Syndrome
    Role: Principal Investigator
    R21AI079616     (KOVATS, SUSAN)Aug 15, 2008 - Jul 31, 2011
    NIH
    Do estrogen receptors in B cells and DC mediate sex bias in murine lupus?
    Role: Co-Principal Investigator
    R01GM063497     (FARRIS, A. DARISE)Aug 1, 2002 - Jul 31, 2006
    NIH
    Can Somatic Mutations Mediate Anti-La Autoimmunity
    Role: Principal Investigator
    K02AI051647     (FARRIS, A. DARISE)Apr 1, 2002 - Mar 31, 2008
    NIH
    Tolerance to the Nuclear Antigen La
    Role: Principal Investigator
    R01AI048097     (FARRIS, A DARISE)Apr 15, 2001 - May 31, 2014
    NIH
    T Cell Tolerance & Autoimmunity to Nuclear Antigen La
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mytych JS, Pan Z, Lopez-Davis C, Redinger N, Lawrence C, Ziegler J, Popescu NI, James JA, Farris AD. Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3. Immunohorizons. 2024 Mar 01; 8(3):269-280. PMID: 38517345; PMCID: PMC10985058.
      Citations:    Fields:    Translation:HumansCells
    2. Warner B, Pranzatelli T, Perez P, Ku A, Matuck BF, Huynh K, Sakai S, Abed M, Jang SI, Yamada E, Dominick K, Ahmed Z, Oliver A, Wasikowski R, Easter Q, Magone MT, Baer A, Pelayo E, Khavandgar Z, Gupta S, Kleiner D, Lessard C, Farris A, Martin D, Morell R, Zheng C, Rachmaninoff N, Maldonado-Ortiz J, Qu X, Aure M, Dezfulian M, Lake R, Teichmann S, Barber D, Tsoi L, Sowalsky A, Tyc K, Gudjonsson J, Byrd K, Johnson P, Liu J, Chiorini J. GZMK+CD8+ T cells Target a Specific Acinar Cell Type in Sj?gren's Disease. Res Sq. 2023 Dec 19. PMID: 38196575; PMCID: PMC10775371.
      Citations: 4     
    3. Brito-Zer?n P, Flores-Ch?vez A, Ng WF, Fanny Horv?th I, Rasmussen A, Priori R, Baldini C, Armagan B, ?zkiziltas B, Praprotnik S, Suzuki Y, Quartuccio L, Hernandez-Molina G, Abacar K, Bartoloni E, Rischmueller M, Reis-de Oliveira F, Fernandes Mo?a Trevisani V, Jurcut C, Fugmann C, Carubbi F, Hofauer B, Valim V, Pasoto SG, Retamozo S, Atzeni F, Fonseca-Aizpuru E, L?pez-Dupla M, Giacomelli R, Nakamura H, Akasbi M, Thompson K, Sz?nt? A, Farris AD, Villa M, Bombardieri S, Kilic L, Tufan A, Perdan Pirkmajer K, Fujisawa Y, de Vita S, Inanc N, Ramos-Casals M, Sj?gren Big Data Consortium. Exposure to air pollution as an environmental determinant of how Sj?gren's disease is expressed at diagnosis. Clin Exp Rheumatol. 2023 Dec; 41(12):2448-2457. PMID: 38019154.
      Citations:    Fields:    Translation:HumansPHPublic Health
    4. Dezfulian MH, Kula T, Pranzatelli T, Kamitaki N, Meng Q, Khatri B, Perez P, Xu Q, Chang A, Kohlgruber AC, Leng Y, Jupudi AA, Joachims ML, Chiorini JA, Lessard CJ, Darise Farris A, Muthuswamy SK, Warner BM, Elledge SJ. TScan-II: A genome-scale platform for the de novo identification of CD4+ T?cell epitopes. Cell. 2023 Dec 07; 186(25):5569-5586.e21. PMID: 38016469.
      Citations: 5     Fields:    Translation:HumansCells
    5. Flores-Ch?vez A, Brito-Zer?n P, Ng WF, Sz?nt? A, Rasmussen A, Priori R, Baldini C, Armagan B, ?zkiziltas B, Praprotnik S, Suzuki Y, Quartuccio L, Hern?ndez-Molina G, Inanc N, Bartoloni E, Rischmueller M, Reis-de Oliveira F, Fernandes Mo?a Trevisani V, Jurcut C, Nordmark G, Carubbi F, Hofauer B, Valim V, Pasoto SG, Retamozo S, Atzeni F, Fonseca-Aizpuru E, L?pez-Dupla M, Giacomelli R, Nakamura H, Akasbi M, Thompson K, Fanny Horv?th I, Farris AD, Simoncelli E, Bombardieri S, Kilic L, Tufan A, Perdan Pirkmajer K, Fujisawa Y, De Vita S, Abacar K, Ramos-Casals M, Sj?gren Big Data Consortium. Influence of exposure to climate-related hazards in the phenotypic expression of primary Sj?gren's syndrome. Clin Exp Rheumatol. 2023 Dec; 41(12):2437-2447. PMID: 38019164.
      Citations: 1     Fields:    Translation:Humans
    6. Wiley MM, Khatri B, Joachims ML, Tessneer KL, Stolarczyk AM, Rasmussen A, Anaya JM, Aqrawi LA, Bae SC, Baecklund E, Bj?rk A, Brun JG, Bucher SM, Dand N, Eloranta ML, Engelke F, Forsblad-d'Elia H, Fugmann C, Glenn SB, Gong C, Gottenberg JE, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kelly JA, Khanam S, Kim K, Kvarnstr?m M, Mandl T, Mart?n J, Morris DL, Nocturne G, Norheim KB, Olsson P, Palm ?, Pers JO, Rhodus NL, Sj?wall C, Skarstein K, Taylor KE, Tombleson P, Thorlacius GE, Venuturupalli S, Vital EM, Wallace DJ, Grundahl KM, Radfar L, Brennan MT, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Appel S, Eriksson P, Bowman SJ, Omdal R, R?nnblom L, Warner BM, Rischmueller M, Witte T, Farris AD, Mariette X, Shiboski CH, Sj?gren?s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius M, Alarc?n-Riquelme ME, PRECISESADS Clinical Consortium, Ng WF, UK Primary Sj?gren?s Syndrome Registry, Sivils KL, Guthridge JM, Adrianto I, Vyse TJ, Tsao BP, Nordmark G, Lessard CJ. Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland. bioRxiv. 2023 Oct 06. PMID: 39071447; PMCID: PMC11275775.
      Citations:    
    7. Brito-Zer?n P, Flores-Ch?vez A, Horv?th IF, Rasmussen A, Li X, Olsson P, Vissink A, Priori R, Armagan B, Hernandez-Molina G, Praprotnik S, Quartuccio L, Inan? N, ?zkiziltas B, Bartoloni E, Sebastian A, Rom?o VC, Solans R, Pasoto SG, Rischmueller M, Galisteo C, Suzuki Y, Trevisani VFM, Fugmann C, Gonz?lez-Garc?a A, Carubbi F, Jurcut C, Shimizu T, Retamozo S, Atzeni F, Hofauer B, Melchor-D?az S, Gheita T, L?pez-Dupla M, Fonseca-Aizpuru E, Giacomelli R, V?zquez M, Consani S, Akasbi M, Nakamura H, Sz?nt? A, Farris AD, Wang L, Mandl T, Gattamelata A, Kilic L, Pirkmajer KP, Abacar K, Tufan A, de Vita S, Bootsma H, Ramos-Casals M, Sj?gren Big Data Consortium. Mortality risk factors in primary Sj?gren syndrome: a?real-world, retrospective, cohort study. EClinicalMedicine. 2023 Jul; 61:102062. PMID: 37457113; PMCID: PMC10344811.
      Citations: 2     
    8. Longobardi S, Lopez-Davis C, Khatri B, Georgescu C, Pritchett-Frazee C, Lawrence C, Rasmussen A, Radfar L, Scofield RH, Baer AN, Robinson SA, Darrah E, Axtell RC, Pardo G, Wren JD, Koelsch KA, Guthridge JM, James JA, Lessard CJ, Farris AD. Autoantibodies identify primary Sj?gren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B. Ann Rheum Dis. 2023 May 05. PMID: 37147113.
      Citations: 1     Fields:    Translation:Humans
    9. Mytych JS, Pan Z, Lopez-Davis C, Redinger N, Lawrence C, Ziegler J, Popescu N, James JA, Farris AD. Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3. bioRxiv. 2023 Apr 03. PMID: 37066181; PMCID: PMC10103956.
      Citations:    
    10. Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnstr?m M, Kelly JA, Li H, Mandl T, Mart?n J, Nocturne G, Norheim KB, Palm ?, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, R?nnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME, PRECISESADS Clinical Consortium, Shiboski CH, Sj?gren?s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius M, Ng WF, UK Primary Sj?gren?s Syndrome Registry, Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Author Correction: Genome-wide association study identifies Sj?gren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2023 Feb 03; 14(1):598. PMID: 36737443; PMCID: PMC9898295.
      Citations:    Fields:    
    11. Joachims ML, Khatri B, Li C, Tessneer KL, Ice JA, Stolarczyk AM, Means N, Grundahl KM, Glenn SB, Kelly JA, Lewis DM, Radfar L, Stone DU, Guthridge JM, James JA, Scofield RH, Wiley GB, Wren JD, Gaffney PM, Montgomery CG, Sivils KL, Rasmussen A, Farris AD, Adrianto I, Lessard CJ. Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses. RMD Open. 2022 Nov; 8(2). PMID: 36456101.
      Citations: 6     Translation:Humans
    12. Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnström M, Kelly JA, Li H, Mandl T, Martín J, Nocturne G, Norheim KB, Palm Ø, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME, PRECISESADS Clinical Consortium, Shiboski CH, Sjögren’s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius M, Ng WF, UK Primary Sjögren’s Syndrome Registry, Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 Oct 31; 13(1):6519. PMID: 36316359; PMCID: PMC9622850.
      Citations: 2     Fields:    
    13. Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnström M, Kelly JA, Li H, Mandl T, Martín J, Nocturne G, Norheim KB, Palm Ø, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME, Shiboski CH, Wahren-Herlenius M, Ng WF, Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 07 27; 13(1):4287. PMID: 35896530.
      Citations: 27     Fields:    Translation:Humans
    14. Berndt N, Bippes CC, Michalk I, Bartsch T, Arndt C, Puentes-Cala E, Soto JA, Loureiro LR, Kegler A, Bachmann D, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Bergmann R, Schmitz M, Feldmann A, Bachmann MP. And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling. Int J Mol Sci. 2021 Sep 08; 22(18). PMID: 34575862.
      Citations: 5     Fields:    Translation:HumansCells
    15. Witas R, Rasmussen A, Scofield RH, Radfar L, Stone DU, Grundahl K, Lewis D, Sivils KL, Lessard CJ, Farris AD, Nguyen CQ. Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor. Int J Mol Sci. 2021 Sep 08; 22(18). PMID: 34575873.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    16. Berndt N, Bippes CC, Michalk I, Bachmann D, Bachmann J, Puentes-Cala E, Bartsch T, Loureiro LR, Kegler A, Bergmann R, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Schmitz M, Fahmy K, Feldmann A, Arndt C, Bachmann MP. Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner. Int J Mol Sci. 2021 Mar 25; 22(7). PMID: 33806091.
      Citations: 6     Fields:    Translation:HumansCells
    17. Bachmann MP, Bartsch T, Bippes CC, Bachmann D, Puentes-Cala E, Bachmann J, Bartsch H, Arndt C, Koristka S, Loureiro LR, Kegler A, Laube M, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Schmitz M, Feldmann A. T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation. Int J Mol Sci. 2021 Jan 26; 22(3). PMID: 33530489.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA. Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome. Front Immunol. 2020; 11:606268. PMID: 33488608.
      Citations: 21     Fields:    Translation:HumansCells
    19. Mytych JS, Pan Z, Farris AD. Efferocytosis and Anthrax: Implications for Bacterial Sepsis? J Cell Immunol. 2021; 3(3):133-139. PMID: 34708219.
      Citations:    
    20. Farris AD, Guthridge JM. Overlapping B cell pathways in severe COVID-19 and lupus. Nat Immunol. 2020 12; 21(12):1478-1480. PMID: 33139917.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    21. Joachims ML, Leehan KM, Dozmorov MG, Georgescu C, Pan Z, Lawrence C, Marlin MC, Macwana S, Rasmussen A, Radfar L, Lewis DM, Stone DU, Grundahl K, Scofield RH, Lessard CJ, Wren JD, Thompson LF, Guthridge JM, Sivils KL, Moore JS, Farris AD. Sjögren's Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile. J Clin Med. 2020 Jul 08; 9(7). PMID: 32650575.
      Citations: 12     
    22. Dumas EK, Demiraslan H, Ingram RJ, Sparks RM, Muns E, Zamora A, Larabee J, Garman L, Ballard JD, Boons GJ, James JA, Kayabas U, Doganay M, Farris AD. Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS One. 2020; 15(4):e0230782. PMID: 32294093.
      Citations: 2     Fields:    Translation:HumansCells
    23. Pan Z, Dumas EK, Lawrence C, Pate L, Longobardi S, Wang X, James JA, Kovats S, Farris AD. Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling. Int J Mol Sci. 2019 Mar 07; 20(5). PMID: 30866434.
      Citations: 6     Fields:    Translation:HumansCells
    24. Koelsch KA, Cavett J, Smith K, Moore JS, Lehoux SD, Jia N, Mather T, Quadri SMS, Rasmussen A, Kaufman CE, Lewis DM, Radfar L, Scordino TA, Lessard CJ, Kurien BT, Cummings RD, James JA, Sivils KL, Farris AD, Scofield RH. Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome. Arthritis Rheumatol. 2018 07; 70(7):1102-1113. PMID: 29457375.
      Citations: 3     Fields:    Translation:HumansCells
    25. Dumas EK, Gross T, Larabee J, Pate L, Cuthbertson H, Charlton S, Hallis B, Engler RJM, Collins LC, Spooner CE, Chen H, Ballard J, James JA, Farris AD. Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients. Clin Vaccine Immunol. 2017 Nov; 24(11). PMID: 28877928.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    26. Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Scofield RH, Sivils KL, Montgomery C, Farris AD. Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging. Clin Exp Rheumatol. 2018 May-Jun; 36 Suppl 112(3):80-88. PMID: 29148407.
      Citations: 38     Fields:    Translation:Humans
    27. Leehan KM, Pezant NP, Rasmussen A, Grundahl K, Moore JS, Radfar L, Lewis DM, Stone DU, Lessard CJ, Rhodus NL, Segal BM, Kaufman CE, Scofield RH, Sivils KL, Montgomery C, Farris AD. Fatty infiltration of the minor salivary glands is a selective feature of aging but not Sjögren's syndrome. Autoimmunity. 2017 Dec; 50(8):451-457. PMID: 28988489.
      Citations: 10     Fields:    Translation:Humans
    28. Li H, Reksten TR, Ice JA, Kelly JA, Adrianto I, Rasmussen A, Wang S, He B, Grundahl KM, Glenn SB, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Cunninghame Graham DS, Patel K, Adler AJ, Farris AD, Brennan MT, Chodosh J, Gopalakrishnan R, Weisman MH, Venuturupalli S, Wallace DJ, Hefner KS, Houston GD, Huang AJW, Hughes PJ, Lewis DM, Radfar L, Vista ES, Edgar CE, Rohrer MD, Stone DU, Vyse TJ, Harley JB, Gaffney PM, James JA, Turner S, Alevizos I, Anaya JM, Rhodus NL, Segal BM, Montgomery CG, Scofield RH, Kovats S, Mariette X, Rönnblom L, Witte T, Rischmueller M, Wahren-Herlenius M, Omdal R, Jonsson R, Ng WF, Nordmark G, Lessard CJ, Sivils KL. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet. 2017 Jun; 13(6):e1006820. PMID: 28640813.
      Citations: 40     Fields:    Translation:HumansCells
    29. Dumas EK, Garman L, Cuthbertson H, Charlton S, Hallis B, Engler RJM, Choudhari S, Picking WD, James JA, Farris AD. Lethal factor antibodies contribute to lethal toxin neutralization in recipients of anthrax vaccine precipitated. Vaccine. 2017 06 08; 35(26):3416-3422. PMID: 28504191.
      Citations: 11     Fields:    Translation:Humans
    30. Garman L, Smith K, Muns EE, Velte CA, Spooner CE, Munroe ME, Farris AD, Nelson MR, Engler RJ, James JA. Unique Inflammatory Mediators and Specific IgE Levels Distinguish Local from Systemic Reactions after Anthrax Vaccine Adsorbed Vaccination. Clin Vaccine Immunol. 2016 08; 23(8):664-71. PMID: 27280620.
      Citations: 2     Fields:    Translation:Humans
    31. Pan ZJ, Horton CG, Lawrence C, Farris AD. Plasmacytoid dendritic cells and type 1 interferon promote peripheral expansion of forkhead box protein 3(+) regulatory T cells specific for the ubiquitous RNA-binding nuclear antigen La/Sjögren's syndrome (SS)-B. Clin Exp Immunol. 2016 10; 186(1):18-29. PMID: 27227559.
      Citations: 3     Fields:    Translation:AnimalsCells
    32. Joachims ML, Leehan KM, Lawrence C, Pelikan RC, Moore JS, Pan Z, Rasmussen A, Radfar L, Lewis DM, Grundahl KM, Kelly JA, Wiley GB, Shugay M, Chudakov DM, Lessard CJ, Stone DU, Scofield RH, Montgomery CG, Sivils KL, Thompson LF, Farris AD. Single-cell analysis of glandular T cell receptors in Sjögren's syndrome. JCI Insight. 2016 Jun 02; 1(8). PMID: 27358913.
      Citations: 24     Fields:    
    33. Edgar CE, Terrell DR, Vesely SK, Wren JD, Dozmorov IM, Niewold TB, Brown M, Zhou F, Frank MB, Merrill JT, Kremer Hovinga JA, Lämmle B, James JA, George JN, Farris AD. Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura. PLoS One. 2015; 10(2):e0117614. PMID: 25671313.
      Citations: 2     Fields:    Translation:HumansCells
    34. Yaciuk JC, Pan Y, Schwarz K, Pan ZJ, Maier-Moore JS, Kosanke SD, Lawrence C, Farris AD. Defective selection of thymic regulatory T cells accompanies autoimmunity and pulmonary infiltrates in Tcra-deficient mice double transgenic for human La/Sjögren's syndrome-B and human La-specific TCR. J Immunol. 2015 Feb 15; 194(4):1514-22. PMID: 25582858.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    35. Maier-Moore JS, Koelsch KA, Smith K, Lessard CJ, Radfar L, Lewis D, Kurien BT, Wolska N, Deshmukh U, Rasmussen A, Sivils KL, James JA, Farris AD, Scofield RH. Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome. Arthritis Rheumatol. 2014 Dec; 66(12):3445-56. PMID: 25199908.
      Citations: 19     Fields:    Translation:HumansCells
    36. Maier-Moore JS, Horton CG, Mathews SA, Confer AW, Lawrence C, Pan Z, Coggeshall KM, Farris AD. Interleukin-6 deficiency corrects nephritis, lymphocyte abnormalities, and secondary Sjögren's syndrome features in lupus-prone Sle1.Yaa mice. Arthritis Rheumatol. 2014 Sep; 66(9):2521-31. PMID: 24891301.
      Citations: 14     Fields:    Translation:AnimalsCells
    37. Garman L, Smith K, Farris AD, Nelson MR, Engler RJ, James JA. Protective antigen-specific memory B cells persist years after anthrax vaccination and correlate with humoral immunity. Toxins (Basel). 2014 Aug 13; 6(8):2424-31. PMID: 25123559.
      Citations: 5     Fields:    Translation:HumansCells
    38. Altorok N, Coit P, Hughes T, Koelsch KA, Stone DU, Rasmussen A, Radfar L, Scofield RH, Sivils KL, Farris AD, Sawalha AH. Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome. Arthritis Rheumatol. 2014 Mar; 66(3):731-9. PMID: 24574234.
      Citations: 78     Fields:    Translation:HumansCells
    39. Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. Nat Genet. 2013 Nov; 45(11):1284-92. PMID: 24097067.
      Citations: 229     Fields:    Translation:Humans
    40. Rasmussen A, Ice JA, Li H, Grundahl K, Kelly JA, Radfar L, Stone DU, Hefner KS, Anaya JM, Rohrer M, Gopalakrishnan R, Houston GD, Lewis DM, Chodosh J, Harley JB, Hughes P, Maier-Moore JS, Montgomery CG, Rhodus NL, Farris AD, Segal BM, Jonsson R, Lessard CJ, Scofield RH, Sivils KL. Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort. Ann Rheum Dis. 2014 Jan; 73(1):31-8. PMID: 23968620.
      Citations: 77     Fields:    Translation:HumansCells
    41. Dumas EK, Nguyen ML, Cox PM, Rodgers H, Peterson JL, James JA, Farris AD. Stochastic humoral immunity to Bacillus anthracis protective antigen: identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization. Vaccine. 2013 Apr 03; 31(14):1856-63. PMID: 23415781.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    42. Andrews SF, Zhang Q, Lim S, Li L, Lee JH, Zheng NY, Huang M, Taylor WM, Farris AD, Ni D, Meng W, Luning Prak ET, Wilson PC. Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. J Exp Med. 2013 Jan 14; 210(1):125-42. PMID: 23267014.
      Citations: 14     Fields:    Translation:AnimalsCells
    43. Garman L, Dumas EK, Kurella S, Hunt JJ, Crowe SR, Nguyen ML, Cox PM, James JA, Farris AD. MHC class II and non-MHC class II genes differentially influence humoral immunity to Bacillus anthracis lethal factor and protective antigen. Toxins (Basel). 2012 Dec; 4(12):1451-67. PMID: 23342680.
      Citations: 3     Fields:    Translation:AnimalsPHPublic Health
    44. Smith K, Crowe SR, Garman L, Guthridge CJ, Muther JJ, McKee E, Zheng NY, Farris AD, Guthridge JM, Wilson PC, James JA. Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization. Vaccine. 2012 Jun 13; 30(28):4276-83. PMID: 22425791.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    45. Horton CG, Farris AD. Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention. Curr Allergy Asthma Rep. 2012 Feb; 12(1):1-7. PMID: 22086298.
      Citations: 10     Fields:    Translation:HumansAnimals
    46. Dumas EK, Cox PM, Fullenwider CO, Nguyen M, Centola M, Frank MB, Dozmorov I, James JA, Farris AD. Anthrax lethal toxin-induced gene expression changes in mouse lung. Toxins (Basel). 2011 09; 3(9):1111-30. PMID: 22039574.
      Citations: 4     Fields:    Translation:Animals
    47. Crowe SR, Garman L, Engler RJ, Farris AD, Ballard JD, Harley JB, James JA. Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine. 2011 May 09; 29(20):3670-8. PMID: 21420416.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    48. Horton CG, Pan ZJ, Farris AD. Targeting Toll-like receptors for treatment of SLE. Mediators Inflamm. 2010; 2010. PMID: 20886024.
      Citations: 27     Fields:    Translation:HumansAnimals
    49. Crowe SR, Ash LL, Engler RJ, Ballard JD, Harley JB, Farris AD, James JA. Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge. J Infect Dis. 2010 Jul 15; 202(2):251-60. PMID: 20533877.
      Citations: 26     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    50. Charles E, Joshi S, Ash JD, Fox BA, Farris AD, Bzik DJ, Lang ML, Blader IJ. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect Immun. 2010 Aug; 78(8):3484-92. PMID: 20498261.
      Citations: 12     Fields:    Translation:AnimalsCells
    51. Nguyen ML, Terzyan S, Ballard JD, James JA, Farris AD. The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. Infect Immun. 2009 Nov; 77(11):4714-23. PMID: 19720758.
      Citations: 15     Fields:    Translation:AnimalsCells
    52. Pan ZJ, Maier S, Schwarz K, Azbill J, Akira S, Uematsu S, Farris AD. Toll-like receptor 7 (TLR7) modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells. Ann Rheum Dis. 2010 Jun; 69(6):1195-9. PMID: 19674980.
      Citations: 11     Fields:    Translation:AnimalsCells
    53. Maeda K, Malykhin A, Teague-Weber BN, Sun XH, Farris AD, Coggeshall KM. Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood. 2009 May 07; 113(19):4534-40. PMID: 19224760.
      Citations: 55     Fields:    Translation:AnimalsCells
    54. Duty JA, Szodoray P, Zheng NY, Koelsch KA, Zhang Q, Swiatkowski M, Mathias M, Garman L, Helms C, Nakken B, Smith K, Farris AD, Wilson PC. Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. J Exp Med. 2009 Jan 16; 206(1):139-51. PMID: 19103878.
      Citations: 118     Fields:    Translation:HumansCells
    55. Nguyen ML, Crowe SR, Kurella S, Teryzan S, Cao B, Ballard JD, James JA, Farris AD. Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies. Infect Immun. 2009 Jan; 77(1):162-9. PMID: 18981257.
      Citations: 18     Fields:    Translation:AnimalsCells
    56. Van Komen JS, Mishra S, Byrum J, Chichili GR, Yaciuk JC, Farris AD, Rodgers W. Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals. J Immunol. 2007 Nov 15; 179(10):6845-55. PMID: 17982075.
      Citations: 8     Fields:    Translation:AnimalsCells
    57. Dudek NL, Maier S, Chen ZJ, Mudd PA, Mannering SI, Jackson DC, Zeng W, Keech CL, Hamlin K, Pan ZJ, Davis-Schwarz K, Workman-Azbill J, Bachmann M, McCluskey J, Farris AD. T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201. Arthritis Rheum. 2007 Oct; 56(10):3387-98. PMID: 17907193.
      Citations: 12     Fields:    Translation:Animals
    58. Semsei I, Maier S, Workman-Azbill J, Urbán L, Moser K, Zeher M, Bachmann M, Farris AD. Detection of a rare oligo(A) repeat tract mutation (8As-->7As) in the sequence encoding the La/SS-B autoantigen. Anal Biochem. 2007 Nov 01; 370(1):47-53. PMID: 17663983.
      Citations: 1     Fields:    Translation:HumansCells
    59. Teague BN, Pan Y, Mudd PA, Nakken B, Zhang Q, Szodoray P, Kim-Howard X, Wilson PC, Farris AD. Cutting edge: Transitional T3 B cells do not give rise to mature B cells, have undergone selection, and are reduced in murine lupus. J Immunol. 2007 Jun 15; 178(12):7511-5. PMID: 17548583.
      Citations: 36     Fields:    Translation:AnimalsCells
    60. Maier SM, Gross JK, Hamlin KL, Maier JL, Workman JL, Kim-Howard XR, Schoeb TR, Farris AD. Proteinuria of nonautoimmune origin in wild-type FVB/NJ mice. Comp Med. 2007 Jun; 57(3):255-66. PMID: 17605340.
      Citations: 5     Fields:    Translation:AnimalsCells
    61. Shankar M, Nixon JC, Maier S, Workman J, Farris AD, Webb CF. Anti-nuclear antibody production and autoimmunity in transgenic mice that overexpress the transcription factor Bright. J Immunol. 2007 Mar 01; 178(5):2996-3006. PMID: 17312145.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    62. Mudd PA, Teague BN, Farris AD. Regulatory T cells and systemic lupus erythematosus. Scand J Immunol. 2006 Sep; 64(3):211-8. PMID: 16918689.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    63. Bachmann MP, Bartsch H, Gross JK, Maier SM, Gross TF, Workman JL, James JA, Farris AD, Jung B, Franke C, Conrad K, Schmitz M, Büttner C, Buyon JP, Semsei I, Harley JB, Rieber EP. Autoimmunity as a result of escape from RNA surveillance. J Immunol. 2006 Aug 01; 177(3):1698-707. PMID: 16849479.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    64. Tampellini M, Berruti A, Bitossi R, Gorzegno G, Alabiso I, Bottini A, Farris A, Donadio M, Sarobba MG, Manzin E, Durando A, Defabiani E, De Matteis A, Ardine M, Castiglione F, Danese S, Bertone E, Alabiso O, Massobrio M, Dogliotti L. Prognostic significance of changes in CA 15-3 serum levels during chemotherapy in metastatic breast cancer patients. Breast Cancer Res Treat. 2006 Aug; 98(3):241-8. PMID: 16670941.
      Citations: 17     Fields:    Translation:Humans
    65. Pan ZJ, Davis K, Maier S, Bachmann MP, Kim-Howard XR, Keech C, Gordon TP, McCluskey J, Farris AD. Neo-epitopes are required for immunogenicity of the La/SS-B nuclear antigen in the context of late apoptotic cells. Clin Exp Immunol. 2006 Feb; 143(2):237-48. PMID: 16412047.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    66. Kurella S, Yaciuk JC, Dozmorov I, Frank MB, Centola M, Farris AD. Transcriptional modulation of TCR, Notch and Wnt signaling pathways in SEB-anergized CD4+ T cells. Genes Immun. 2005 Oct; 6(7):596-608. PMID: 16034473.
      Citations: 8     Fields:    Translation:AnimalsCells
    67. Nakken B, Davis KE, Pan ZJ, Bachmann M, Farris AD. T-helper cell tolerance to ubiquitous nuclear antigens. Scand J Immunol. 2003 Nov; 58(5):478-92. PMID: 14629620.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    68. Kaufman KM, Farris AD, Gross JK, Kirby MY, Harley JB. Characterization and genomic sequence of the murine 60 kD Ro gene. Genes Immun. 2000; 1(4):265-70. PMID: 11196703.
      Citations: 1     Fields:    Translation:AnimalsCells
    69. Farris AD, Koelsch G, Pruijn GJ, van Venrooij WJ, Harley JB. Conserved features of Y RNAs revealed by automated phylogenetic secondary structure analysis. Nucleic Acids Res. 1999 Feb 15; 27(4):1070-8. PMID: 9927741.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    70. Scofield RH, Farris AD, Horsfall AC, Harley JB. Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins. Arthritis Rheum. 1999 Feb; 42(2):199-209. PMID: 10025913.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    71. James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJ, Harley JB. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest. 1997 Dec 15; 100(12):3019-26. PMID: 9399948.
      Citations: 146     Fields:    Translation:HumansCells
    72. Farris AD, Puvion-Dutilleul F, Puvion E, Harley JB, Lee LA. The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs: association with novel electron-dense bodies. Proc Natl Acad Sci U S A. 1997 Apr 01; 94(7):3040-5. PMID: 9096342.
      Citations: 14     Fields:    Translation:HumansCells
    73. Farris AD, Gross JK, Hanas JS, Harley JB. Genes for murine Y1 and Y3 Ro RNAs have class 3 RNA polymerase III promoter structures and are unlinked on mouse chromosome 6. Gene. 1996 Sep 26; 174(1):35-42. PMID: 8863726.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    74. Farris AD, O'Brien CA, Harley JB. Y3 is the most conserved small RNA component of Ro ribonucleoprotein complexes in vertebrate species. Gene. 1995 Mar 10; 154(2):193-8. PMID: 7534247.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
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