"Chagas Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
Descriptor ID |
D014355
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MeSH Number(s) |
C03.752.300.900.200
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Concept/Terms |
Chagas Disease- Chagas Disease
- Chagas' Disease
- American Trypanosomiasis
- Trypanosomiasis, American
- Trypanosomiasis, South American
- South American Trypanosomiasis
- Trypanosoma cruzi Infection
- Infection, Trypanosoma cruzi
- Infections, Trypanosoma cruzi
- Trypanosoma cruzi Infections
|
Below are MeSH descriptors whose meaning is more general than "Chagas Disease".
Below are MeSH descriptors whose meaning is more specific than "Chagas Disease".
This graph shows the total number of publications written about "Chagas Disease" by people in this website by year, and whether "Chagas Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2021 | 3 | 0 | 3 |
2022 | 3 | 0 | 3 |
2023 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chagas Disease" by people in Profiles.
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Climate change and Trypanosoma cruzi transmission in North and central America. Lancet Microbe. 2024 Oct; 5(10):100946.
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Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease. Nat Commun. 2023 10 25; 14(1):6769.
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Single-Cell Mass Spectrometry Enables Insight into Heterogeneity in Infectious Disease. Anal Chem. 2022 08 02; 94(30):10567-10572.
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Chagas disease in Oklahoma. Am J Med Sci. 2022 Nov; 364(5):521-528.
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Chemical Cartography Approaches to Study Trypanosomatid Infection. J Vis Exp. 2022 01 21; (179).
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Mortality risk in chronic Chagas cardiomyopathy: a systematic review and meta-analysis. ESC Heart Fail. 2021 12; 8(6):5466-5481.
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Central role of metabolism in Trypanosoma cruzi tropism and Chagas disease pathogenesis. Curr Opin Microbiol. 2021 10; 63:204-209.
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Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. ACS Infect Dis. 2021 06 11; 7(6):1638-1649.
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Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease. Sci Adv. 2020 07; 6(30):eaaz2015.
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Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome. PLoS Negl Trop Dis. 2018 03; 12(3):e0006344.