"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endothelins" by people in Profiles.
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Current status of the role of endothelins in regulating ovarian follicular function: A review. Anim Reprod Sci. 2017 Nov; 186:1-10.
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Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling? Antioxid Redox Signal. 2006 Jul-Aug; 8(7-8):1121-9.
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Bimodal distribution of soluble endothelial protein C receptor levels in healthy populations. J Thromb Haemost. 2003 Apr; 1(4):855-6.
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Endothelin and prostaglandin H(2)/thromboxane A(2) enhance myogenic constriction in hypertension by increasing Ca(2+) sensitivity of arteriolar smooth muscle. Hypertension. 2000 Nov; 36(5):856-61.
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Regulation of rDNA transcription during endothelin-1-induced hypertrophy of neonatal cardiomyocytes. Hyperphosphorylation of upstream binding factor, an rDNA transcription factor. Circ Res. 1996 Mar; 78(3):354-61.
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Cloning and characterization of an endothelin-3 specific receptor (ETC receptor) from Xenopus laevis dermal melanophores. J Biol Chem. 1993 Sep 05; 268(25):19126-33.