Glycogen Synthase Kinase 3
"Glycogen Synthase Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.
| Descriptor ID |
D038362
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| MeSH Number(s) |
D05.500.117.875 D08.811.913.696.620.682.700.429.500 D08.811.913.696.620.682.700.646.625 D12.644.360.300.500 D12.776.476.081.875 D12.776.476.300.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3" by people in this website by year, and whether "Glycogen Synthase Kinase 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3" by people in Profiles.
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GSK3-ARC/Arg3.1 and GSK3-Wnt signaling axes trigger amyloid-ß accumulation and neuroinflammation in middle-aged Shugoshin 1 mice. Aging Cell. 2020 10; 19(10):e13221.
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The apoptotic effect of GSK-3 inhibitors: BIO and CHIR 98014 on H1975 lung cancer cells through ROS generation and mitochondrial dysfunction. Biotechnol Lett. 2020 Aug; 42(8):1351-1368.
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GSK-3 Inhibitors: A Double-Edged Sword? - An Update on Tideglusib. Drug Res (Stuttg). 2018 Aug; 68(8):436-443.
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Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells. J Environ Pathol Toxicol Oncol. 2017; 36(4):321-344.
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Resveratrol triggers ER stress-mediated apoptosis by disrupting N-linked glycosylation of proteins in ovarian cancer cells. Cancer Lett. 2016 Feb 28; 371(2):347-53.
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A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/ß-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34.
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Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling. J Invest Dermatol. 2014 Jun; 134(6):1725-1734.
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Reg4-induced mitogenesis involves Akt-GSK3ß-ß-Catenin-TCF-4 signaling in human colorectal cancer. Mol Carcinog. 2014 Feb; 53 Suppl 1:E169-80.
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Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection. Mitochondrion. 2013 Nov; 13(6):566-76.
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Derivation, characterization, and stable transfection of induced pluripotent stem cells from Fischer344 rats. PLoS One. 2011; 6(11):e27345.