"CD11b Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CD antigen that contains a conserved integrin I-domain which is involved in ligand binding. When combined with CD18 the two subunits form MACROPHAGE-1 ANTIGEN.
| Descriptor ID |
D039481
|
| MeSH Number(s) |
D12.776.395.550.200.074.750 D12.776.543.550.200.093.750 D12.776.543.750.705.408.100.150 D12.776.543.750.705.833.062 D23.050.301.350.074.049
|
| Concept/Terms |
CD11b Antigen- CD11b Antigen
- Antigen, CD11b
- ITGAM Protein
- Integrin alpha M
- alpha M, Integrin
- CD11b Antigens
- Mo1 Antigen
- Antigen, Mo1
- Mo1 Glycoprotein
- Integrin alphaM
- alphaM, Integrin
- alphaM Integrin
- Integrin, alphaM
- Complement Component Receptor 3, alpha
- Antigens, CD11b
|
Below are MeSH descriptors whose meaning is more general than "CD11b Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD11b Antigen".
This graph shows the total number of publications written about "CD11b Antigen" by people in this website by year, and whether "CD11b Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD11b Antigen" by people in Profiles.
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ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico. PLoS One. 2019; 14(11):e0224543.
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Amelioration of ongoing experimental autoimmune encephalomyelitis with fluoxetine. J Neuroimmunol. 2017 12 15; 313:77-81.
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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest. 2017 Apr 03; 127(4):1271-1283.
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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis Rheumatol. 2016 Apr; 68(4):932-43.
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Is the Use of Complete Blood Counts with Manual Differentials an Antiquated Method of Determining Neutrophil Composition in Newborns? Ann Clin Lab Sci. 2015; 45(4):403-13.
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A novel T-cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in mice. Eur J Immunol. 2014 Jul; 44(7):1936-46.
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Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. Hum Mol Genet. 2014 Aug 01; 23(15):4161-76.
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Th17 cells induce Th1-polarizing monocyte-derived dendritic cells. J Immunol. 2013 Aug 01; 191(3):1175-87.
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Integrin CD11b negatively regulates BCR signalling to maintain autoreactive B cell tolerance. Nat Commun. 2013; 4:2813.
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IRF4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation. J Immunol. 2012 Oct 01; 189(7):3368-77.