"Neuropilin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.
| Descriptor ID |
D039943
|
| MeSH Number(s) |
D12.776.543.750.590.750
|
| Concept/Terms |
Neuropilin-2- Neuropilin-2
- Neuropilin 2
- NRP2 Protein
- Npn-2 Protein
- Npn 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Neuropilin-2".
Below are MeSH descriptors whose meaning is more specific than "Neuropilin-2".
This graph shows the total number of publications written about "Neuropilin-2" by people in this website by year, and whether "Neuropilin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuropilin-2" by people in Profiles.
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VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. 2021 02; 40(5):964-979.