"Thioredoxin Reductase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of thioredoxin reductase found primarily in the CYTOSOL.
| Descriptor ID |
D054481
|
| MeSH Number(s) |
D08.811.682.667.750.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thioredoxin Reductase 1".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxin Reductase 1".
This graph shows the total number of publications written about "Thioredoxin Reductase 1" by people in this website by year, and whether "Thioredoxin Reductase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thioredoxin Reductase 1" by people in Profiles.
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Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages. Life Sci. 2020 Oct 15; 259:118285.
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Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia. Oxid Med Cell Longev. 2019; 2019:7945983.
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Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibition. Redox Biol. 2018 10; 19:331-338.
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The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanisms. Am J Physiol Lung Cell Mol Physiol. 2018 10 01; 315(4):L545-L552.
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Aurothioglucose does not improve alveolarization or elicit sustained Nrf2 activation in C57BL/6 models of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2018 05 01; 314(5):L736-L742.
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The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome. Antioxid Redox Signal. 2014 Jun 10; 20(17):2681-91.
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Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2013 Sep; 305(5):L389-95.
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Alterations of the thioredoxin system by hyperoxia: implications for alveolar development. Am J Respir Cell Mol Biol. 2009 Nov; 41(5):612-9.
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Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane. Neurochem Int. 2009 Mar-Apr; 54(3-4):172-9.