Tartrate-Resistant Acid Phosphatase
"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
Descriptor ID |
D000071681
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MeSH Number(s) |
D08.811.277.352.650.025.500 D08.811.277.352.650.625.862
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Concept/Terms |
Tartrate-Resistant Acid Phosphatase- Tartrate-Resistant Acid Phosphatase
- Acid Phosphatase, Tartrate-Resistant
- Phosphatase, Tartrate-Resistant Acid
- Tartrate Resistant Acid Phosphatase
- TRAcP
TRAP Type 5 AcPase- TRAP Type 5 AcPase
- Acid Phosphatase V
- Phosphatase V, Acid
- V, Acid Phosphatase
- AcPase V
- V, AcPase
- Type 5 Acid Phosphatase
- Tartrate-Resistant Acid Phosphatase Type 5
- Tartrate Resistant Acid Phosphatase Type 5
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Below are MeSH descriptors whose meaning is more general than "Tartrate-Resistant Acid Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Tartrate-Resistant Acid Phosphatase".
This graph shows the total number of publications written about "Tartrate-Resistant Acid Phosphatase" by people in this website by year, and whether "Tartrate-Resistant Acid Phosphatase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tartrate-Resistant Acid Phosphatase" by people in Profiles.
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Osteoclast Differentiation Assay. Methods Mol Biol. 2019; 1882:143-148.
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Effects of whole-body vibration on acute bone turnover marker responses to resistance exercise in young men. J Musculoskelet Neuronal Interact. 2015 Mar; 15(1):23-31.
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Hypoxia triggers a HIF-mediated differentiation of peripheral blood mononuclear cells into osteoclasts. Orthod Craniofac Res. 2012 Feb; 15(1):1-9.
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Dried plum polyphenols inhibit osteoclastogenesis by downregulating NFATc1 and inflammatory mediators. Calcif Tissue Int. 2008 Jun; 82(6):475-88.
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Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts. Endocrinology. 2001 Jul; 142(7):2898-905.
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Bovine UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase. II. Enzymatic characterization and identification of the catalytic subunit. J Biol Chem. 1996 Dec 06; 271(49):31446-51.