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Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.
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Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.
Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy. J Biol Chem. 2002 Jun 14; 277(24):21285-90.
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PubMed
subject areas
Alanine
Alanine
Amino Acid Sequence
Amino Acid Sequence
Animals
Animals
Blotting, Northern
Blotting, Northern
Blotting, Western
Blotting, Western
DNA, Complementary
DNA, Complementary
Hypertrophy
Hypertrophy
Insulin-Like Growth Factor Binding Protein 4
Insulin-Like Growth Factor Binding Protein 4
Insulin-Like Growth Factor I
Insulin-Like Growth Factor I
Mice
Mice
Mice, Transgenic
Mice, Transgenic
Models, Genetic
Models, Genetic
Molecular Sequence Data
Molecular Sequence Data
Muscle, Smooth
Muscle, Smooth
Mutation
Mutation
Phenotype
Phenotype
Promoter Regions, Genetic
Promoter Regions, Genetic
Protein Binding
Protein Binding
Protein Structure, Tertiary
Protein Structure, Tertiary
RNA, Messenger
RNA, Messenger
Time Factors
Time Factors
Tissue Distribution
Tissue Distribution
Transgenes
Transgenes