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Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.
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Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.
Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein. Ann Rheum Dis. 2012 Jul; 71(7):1219-26.
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PubMed
subject areas
Biomarkers
Biomarkers
Chromosome Mapping
Chromosome Mapping
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Enzymologic
Genetic Markers
Genetic Markers
Genetic Predisposition to Disease
Genetic Predisposition to Disease
Genotype
Genotype
Half-Life
Half-Life
HEK293 Cells
HEK293 Cells
Humans
Humans
Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
Mutation
Mutation
NF-kappa B
NF-kappa B
Polymorphism, Single Nucleotide
Polymorphism, Single Nucleotide
Protein Binding
Protein Binding
Protein Stability
Protein Stability
src-Family Kinases
src-Family Kinases
Transfection
Transfection
authors with profiles
Jonathan D. Wren