A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis. Invest Ophthalmol Vis Sci. 2013 Jan 07; 54(1):85-95.
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Animals
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Animals
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Antineoplastic Agents
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Antineoplastic Agents
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ATP-Binding Cassette Transporters
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ATP-Binding Cassette Transporters
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Cattle
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Cattle
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Disease Models, Animal
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Disease Models, Animal
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Fenretinide
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Fenretinide
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Humans
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Humans
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Hydrolases
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Hydrolases
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Ligands
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Ligands
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Lipofuscin
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Lipofuscin
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Macular Degeneration
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Macular Degeneration
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Mice
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Mice
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Mice, 129 Strain
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Mice, 129 Strain
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Mice, Mutant Strains
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Mice, Mutant Strains
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Piperidines
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Piperidines
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Prealbumin
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Prealbumin
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Retinoids
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Retinoids
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Retinol-Binding Proteins, Plasma
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Retinol-Binding Proteins, Plasma