cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function.

cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function. J Neurosci. 2013 Sep 11; 33(37):14939-48.

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subject areas

Animals
Animals
Animals, Newborn
Animals, Newborn
Carrier Proteins
Carrier Proteins
Cyclic GMP
Cyclic GMP
Cyclic GMP-Dependent Protein Kinases
Cyclic GMP-Dependent Protein Kinases
Cyclic Nucleotide-Gated Cation Channels
Cyclic Nucleotide-Gated Cation Channels
Enzyme-Linked Immunosorbent Assay
Enzyme-Linked Immunosorbent Assay
Eye Proteins
Eye Proteins
Guanylate Cyclase
Guanylate Cyclase
In Vitro Techniques
In Vitro Techniques
Mice
Mice
Mice, Inbred C57BL
Mice, Inbred C57BL
Mice, Knockout
Mice, Knockout
Nerve Tissue Proteins
Nerve Tissue Proteins
Phosphoric Diester Hydrolases
Phosphoric Diester Hydrolases
Photoreceptor Cells
Photoreceptor Cells
Receptors, Cell Surface
Receptors, Cell Surface
Receptors, N-Methyl-D-Aspartate
Receptors, N-Methyl-D-Aspartate
Retina
Retina
Retinal Degeneration
Retinal Degeneration

authors with profiles

Hongwei Ma