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Identification of small molecules that protect pancreatic ß cells against endoplasmic reticulum stress-induced cell death.
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Identification of small molecules that protect pancreatic ß cells against endoplasmic reticulum stress-induced cell death.
Identification of small molecules that protect pancreatic ß cells against endoplasmic reticulum stress-induced cell death. ACS Chem Biol. 2014 Dec 19; 9(12):2796-806.
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PubMed
subject areas
Adenosine Triphosphate
Adenosine Triphosphate
Animals
Animals
Apoptosis
Apoptosis
Caspase 3
Caspase 3
Cell Line
Cell Line
Cell Survival
Cell Survival
Drug Discovery
Drug Discovery
Endoplasmic Reticulum
Endoplasmic Reticulum
Endoplasmic Reticulum Stress
Endoplasmic Reticulum Stress
Gene Expression
Gene Expression
High-Throughput Screening Assays
High-Throughput Screening Assays
Humans
Humans
Insulin
Insulin
Insulin-Secreting Cells
Insulin-Secreting Cells
Mice
Mice
Palmitic Acid
Palmitic Acid
Primary Cell Culture
Primary Cell Culture
Protective Agents
Protective Agents
Signal Transduction
Signal Transduction
Small Molecule Libraries
Small Molecule Libraries
Stress, Physiological
Stress, Physiological
Tunicamycin
Tunicamycin
Unfolded Protein Response
Unfolded Protein Response
authors with profiles
Hui-Ying Lim
Weidong Wang