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Collybolide is a novel biased agonist of ?-opioid receptors with potent antipruritic activity.
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Collybolide is a novel biased agonist of ?-opioid receptors with potent antipruritic activity.
Collybolide is a novel biased agonist of ?-opioid receptors with potent antipruritic activity. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):6041-6.
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subject areas
Agaricales
Agaricales
Animals
Animals
Antipruritics
Antipruritics
Diterpenes, Clerodane
Diterpenes, Clerodane
HEK293 Cells
HEK293 Cells
Humans
Humans
MAP Kinase Signaling System
MAP Kinase Signaling System
Mice
Mice
Mice, Knockout
Mice, Knockout
Receptors, Opioid, kappa
Receptors, Opioid, kappa
Second Messenger Systems
Second Messenger Systems
authors with profiles
Indrajeet Sharma