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Structure-guided design of an Hsp90ß N-terminal isoform-selective inhibitor.
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Structure-guided design of an Hsp90ß N-terminal isoform-selective inhibitor.
Structure-guided design of an Hsp90ß N-terminal isoform-selective inhibitor. Nat Commun. 2018 01 30; 9(1):425.
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PubMed
subject areas
Antineoplastic Agents
Antineoplastic Agents
Cell Line, Tumor
Cell Line, Tumor
Drug Design
Drug Design
Drug Evaluation, Preclinical
Drug Evaluation, Preclinical
HEK293 Cells
HEK293 Cells
HSP90 Heat-Shock Proteins
HSP90 Heat-Shock Proteins
Humans
Humans
Hydrogen Bonding
Hydrogen Bonding
Protein Isoforms
Protein Isoforms
Structure-Activity Relationship
Structure-Activity Relationship
authors with profiles
Robert Matts