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Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome.
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Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome.
Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome. Dis Model Mech. 2020 03 30; 13(3).
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PubMed
subject areas
Animals
Animals
Animals, Newborn
Animals, Newborn
Apoptosis
Apoptosis
Astrocytes
Astrocytes
Cell Survival
Cell Survival
Disease Models, Animal
Disease Models, Animal
DNA-Binding Proteins
DNA-Binding Proteins
Estradiol
Estradiol
Genetic Diseases, X-Linked
Genetic Diseases, X-Linked
Homeodomain Proteins
Homeodomain Proteins
Humans
Humans
Immunity, Innate
Immunity, Innate
Infant, Newborn
Infant, Newborn
Mice, Inbred C57BL
Mice, Inbred C57BL
Microglia
Microglia
Mutation
Mutation
Neocortex
Neocortex
Nerve Tissue Proteins
Nerve Tissue Proteins
Neurons
Neurons
Spasms, Infantile
Spasms, Infantile
Syndrome
Syndrome
Transcription Factors
Transcription Factors
Trinucleotide Repeat Expansion
Trinucleotide Repeat Expansion