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Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
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Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth. J Biol Chem. 2007 Feb 09; 282(6):3428-32.
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PubMed
subject areas
Amino Acid Substitution
Amino Acid Substitution
Animals
Animals
Cell Line, Tumor
Cell Line, Tumor
Cell Proliferation
Cell Proliferation
Drug Delivery Systems
Drug Delivery Systems
Enzyme Activation
Enzyme Activation
Erlotinib Hydrochloride
Erlotinib Hydrochloride
Growth Inhibitors
Growth Inhibitors
Hematopoietic Stem Cells
Hematopoietic Stem Cells
Humans
Humans
Janus Kinase 2
Janus Kinase 2
Jurkat Cells
Jurkat Cells
Mice
Mice
Phenylalanine
Phenylalanine
Polycythemia Vera
Polycythemia Vera
Protein Kinase Inhibitors
Protein Kinase Inhibitors
Quinazolines
Quinazolines
Valine
Valine
authors with profiles
Zhizhuang Joe Zhao