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Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors.
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Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors.
Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors. Org Lett. 2009 Jun 04; 11(11):2353-6.
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PubMed
subject areas
Adenosine Triphosphatases
Adenosine Triphosphatases
Amides
Amides
Antineoplastic Agents
Antineoplastic Agents
Benzoquinones
Benzoquinones
Drug Design
Drug Design
Drug Screening Assays, Antitumor
Drug Screening Assays, Antitumor
Female
Female
HSP90 Heat-Shock Proteins
HSP90 Heat-Shock Proteins
Humans
Humans
Lactams, Macrocyclic
Lactams, Macrocyclic
Molecular Structure
Molecular Structure
Stereoisomerism
Stereoisomerism
authors with profiles
Adam S Duerfeldt